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Tracing the Origin, Spread, and Molecular Evolution of Zika Virus in Puerto Rico, 2016–2017

by Cruz-López, Fabiola , Kalinich, Chaney C. , Black, Allison , Ellis, Brett , Grubaugh, Nathan D. , Adams, Laura E. , Bedford, Trevor , Santiago, Gilberto A. , Flores, Betzabel , Ellis, Esther , Waterman, Steve H. , Charriez, Keyla N. , Sharp, Tyler M. , Paz-Bailey, Gabriela , Muñoz-Jordán, Jorge L. , González, Glenda L. , Hentoff, Aaron , Fauver, Joseph R.

in Causes of / Datasets / Dengue fever / Disease control / Disease prevention / Distribution / Epidemics / Epidemiology / Evolution, Molecular / Genomes / Genomics / Humans / Medical research / Molecular evolution / next-generation sequencing / NGS / Phylogenetics / Public health / Puerto Rico / Puerto Rico - epidemiology / Research Letter / Severe acute respiratory syndrome / Severe acute respiratory syndrome coronavirus 2 / Tracing the Origin, Spread, and Molecular Evolution of Zika Virus in Puerto Rico, 2016–2017 / Trends / Vector-borne diseases / Virus research / Zika / Zika virus / Zika Virus - genetics / Zika Virus Infection - epidemiology

2021

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Tracing the Origin, Spread, and Molecular Evolution of Zika Virus in Puerto Rico, 2016–2017

2021

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2021

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Journal Article

Tracing the Origin, Spread, and Molecular Evolution of Zika Virus in Puerto Rico, 2016–2017

Cruz-López, Fabiola,

Kalinich, Chaney C.,

Black, Allison,

Ellis, Brett,

Grubaugh, Nathan D.,

Adams, Laura E.,

Bedford, Trevor,

Santiago, Gilberto A.,

Flores, Betzabel,

Ellis, Esther,

Waterman, Steve H.,

Charriez, Keyla N.,

Sharp, Tyler M.,

Paz-Bailey, Gabriela,

Muñoz-Jordán, Jorge L.,

González, Glenda L.,

Hentoff, Aaron,

Fauver, Joseph R.

2021

Overview

We reconstructed the 2016-2017 Zika virus epidemic in Puerto Rico by using complete genomes to uncover the epidemic's origin, spread, and evolutionary dynamics. Our study revealed that the epidemic was propelled by multiple introductions that spread across the island, intricate evolutionary patterns, and ≈10 months of cryptic transmission.

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U.S. National Center for Infectious Diseases,Centers for Disease Control and Prevention

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