Asset Details
Do you wish to reserve the book?
Functional architecture of the foveola revealed in the living primate
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Functional architecture of the foveola revealed in the living primate
Do you wish to request the book?
Functional architecture of the foveola revealed in the living primate
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Functional architecture of the foveola revealed in the living primate
2018
Overview
The primate foveola, with its high cone density and magnified cortical representation, is exquisitely specialized for high-resolution spatial vision. However, uncovering the wiring of retinal circuitry responsible for this performance has been challenging due to the difficulty in recording receptive fields of foveal retinal ganglion cells (RGCs) in vivo. In this study, we use adaptive optics scanning laser ophthalmoscopy (AOSLO) to image the calcium responses of RGCs in the living primate, with a stable, high precision visual stimulus that allowed us to localize the receptive fields of hundreds of foveal ganglion cells. This approach revealed a precisely radial organization of foveal RGCs, despite the many distortions possible during the extended developmental migration of foveal cells. By back projecting the line connecting RGC somas to their receptive fields, we have been able to define the 'physiological center' of the foveola, locating the vertical meridian separating left and right hemifields in vivo.
Publisher
Public Library of Science,Public Library of Science (PLoS)
Subject
/ Animals
/ Brain
/ Calcium
/ Circuits
/ Cortex
/ Fovea Centralis - diagnostic imaging
/ Fovea Centralis - metabolism
/ Lasers
/ Male
/ Medicine and Health Sciences
/ Noise
/ Optics
/ Primates
/ Research and Analysis Methods
/ Retina
/ Retinal Ganglion Cells - cytology
/ Retinal Ganglion Cells - metabolism
/ Tomography, Optical Coherence
/ Wiring
