Asset Details
Do you wish to reserve the book?
Prevention of Activated Neutrophil Adhesion to Endothelium by Soluble Adhesion Protein GMP140
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Prevention of Activated Neutrophil Adhesion to Endothelium by Soluble Adhesion Protein GMP140
Do you wish to request the book?
Prevention of Activated Neutrophil Adhesion to Endothelium by Soluble Adhesion Protein GMP140
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Prevention of Activated Neutrophil Adhesion to Endothelium by Soluble Adhesion Protein GMP140
1990
Overview
Neutrophils and monocytes, but not lymphocytes, adhered strongly to plastic surfaces coated with GMP140, a protein of endothelial cells and platelets. This adhesion of neutrophils was mediated by GMP140 and not by the CD18 integrin complex. By contrast, GMP140 in solution inhibited the CD18-dependent adhesion of tumor necrosis factor-α-activated neutrophils to plastic surfaces and resting endothelium, but not of resting neutrophils to tumor necrosis factor-α-activated endothelium. Thus, the binding of a soluble form of an adhesion protein selectively inhibited another set of adhesive events. Soluble GMP140 may be important in maintaining the nonadhesiveness of neutrophils in the circulation and may serve to limit inflammatory reactions.
Publisher
American Society for the Advancement of Science,American Association for the Advancement of Science
Subject
/ Biological and medical sciences
/ Cell Adhesion - drug effects
/ Endothelium, Vascular - physiology
/ Fundamental and applied biological sciences. Psychology
/ Humans
/ Molecular and cellular biology
/ Plastics
/ Platelet Membrane Glycoproteins - pharmacology
/ Receptors, Leukocyte-Adhesion - immunology
/ Receptors, Leukocyte-Adhesion - physiology
