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Coordination games in cancer
by
Duckett, Derek
, Moffitt Cancer Center [Tampa, FL, USA] (M2C)
, Delft Institute of Applied Mathematics (DIAM) ; Delft University of Technology (TU Delft)
, Bayer, Peter
, Stankova, Katerina
, Gatenby, Robert A
, Toulouse School of Economics (TSE-R) ; Université Toulouse Capitole (UT Capitole) ; Université de Toulouse (UT)-Université de Toulouse (UT)-École des hautes études en sciences sociales (EHESS)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)
, Mcdonald, Patricia
, Brown, Joel
2022
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Coordination games in cancer
by
Duckett, Derek
, Moffitt Cancer Center [Tampa, FL, USA] (M2C)
, Delft Institute of Applied Mathematics (DIAM) ; Delft University of Technology (TU Delft)
, Bayer, Peter
, Stankova, Katerina
, Gatenby, Robert A
, Toulouse School of Economics (TSE-R) ; Université Toulouse Capitole (UT Capitole) ; Université de Toulouse (UT)-Université de Toulouse (UT)-École des hautes études en sciences sociales (EHESS)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)
, Mcdonald, Patricia
, Brown, Joel
in
2022
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Coordination games in cancer
by
Duckett, Derek
, Moffitt Cancer Center [Tampa, FL, USA] (M2C)
, Delft Institute of Applied Mathematics (DIAM) ; Delft University of Technology (TU Delft)
, Bayer, Peter
, Stankova, Katerina
, Gatenby, Robert A
, Toulouse School of Economics (TSE-R) ; Université Toulouse Capitole (UT Capitole) ; Université de Toulouse (UT)-Université de Toulouse (UT)-École des hautes études en sciences sociales (EHESS)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)
, Mcdonald, Patricia
, Brown, Joel
2022
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Journal Article
Coordination games in cancer
2022
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Overview
We propose a model of cancer initiation and progression where tumor growth is modulated by an evolutionary coordination game. Evolutionary games of cancer are widely used to model frequency-dependent cell interactions with the most studied games being the Prisoner’s Dilemma and public goods games. Coordination games, by their more obscure and less evocative nature, are left understudied, despite the fact that, as we argue, they offer great potential in understanding and treating cancer. In this paper we present the conditions under which coordination games between cancer cells evolve, we propose aspects of cancer that can be modeled as results of coordination games, and explore the ways through which coordination games of cancer can be exploited for therapy.
Publisher
CCSD,Public Library of Science,Public Library of Science (PLoS)
ISBN
0007910728000
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