Journal Article

Anti-GABA A receptor encephalitis 14 months after allogeneic haematopoietic stem-cell transplant for acute myeloid leukaemia

Bittner, Jan, MD, Kuhle, Jens, Prof, Mutke, Matthias, MD, Hirsch, Hans H, Prof, Halter, Jörg P, Prof, Rusche, Thilo, MD, Cordier, Dominik, MD, Fisch, Urs, MD PhD, Hench, Jürgen, MD, Rüegg, Stephan, Prof, Grzonka, Pascale, MD, Frank, Nicole, MD, Sutter, Raoul, Prof, Galbusera, Riccardo, MD, Fischer, Urs, Prof, Lieb, Johanna, MD, Yaldizli, Özgür, Prof, Frank, Stephan, Prof, Matteazzi, Francesca, MD, Stelmes, Anne, MD

2024

Overview

Repeated MRIs, from days 5 to 12 after admission, showed progression of the multiple cortico-subcortical lesions ( figure); the EEG showed right-hemispheric temporo-parietal focal slowing independent of the worsening of the patient's condition. UFischer reports research grants from the Swiss National Science Foundation, the Swiss Heart Foundation, Medtronic, Stryker, Penumbra, Rapid medical, Phenox, and Boehringer Ingelheim; consulting fees from Medtronic, Stryker, CSL Behring (fees paid to institution); has membership in a data safety monitoring board for the TITAN trial, IN EXTREMIS trial, LATE-MT trial, Rapid Puls Trial; has membership in the Clinical Event Committee of the COATING Trial (Phenox) and membership in the advisory board for CLS Behring, Acthera, Alexion/Portola, Boehringer Ingelheim (all fees paid to institution); is president of the Swiss Neurological Society. Acknowledgments We thank the patient for his consent and all health-care professionals who were involved in his treatment at the Department of Neurology; Department of Radiology; Department of Intensive Care; Department of Medicine; Department of Anaesthesiology; Institute of Pathology; Department of Neurosurgery; and the Emergency Department of the University Hospital Basel, Switzerland; the REHAB Clinic for Neurorehabilitation, Basel, Switzerland; and the Laboratory Krone, Bad Salzuflen, Germany.

• Publisher: Elsevier Limited
• Subject: Acute myeloid leukemia / Allografts / Anesthesiology / Biopsy / Emergency medical care / Emergency medical services / Encephalitis / Hemispheric laterality / Hospitals / Intensive care / Internal Medicine / Leukemia / Neurology / Neurosurgery / Patients / Radiology / Rehabilitation / Stem cell transplantation / Stem cells / γ-Aminobutyric acid