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Evidence of Zika Virus Infection in Brain and Placental Tissues from Two Congenitally Infected Newborns and Two Fetal Losses — Brazil, 2015

by de Oliveira Ramos, Ana Maria , de Oliveria, Wanderson Kleber , Goldsmith, Cynthia , Luz, Kleber G. , Bhatnagar, Julu , Keating, M. Kelly , Martines, Roosecelis Brasil , Ritter, Jana , Rollin, Dominique , Muehlenbachs, Atis , Gary, Joy , Davi, Helaine Pompeia Freire , Silva-Flannery, Luciana , Lambert, Amy , Hale, Gillian , Shieh, Wun-Ju , Zaki, Sherif , Lanciotti, Robert

in Aedes aegypti / Analysis / Brain / Dengue virus / Flavivirus / Infection / Newborn infants / Notes from the Field / Virus diseases / Zika virus

2016

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Evidence of Zika Virus Infection in Brain and Placental Tissues from Two Congenitally Infected Newborns and Two Fetal Losses — Brazil, 2015

in Aedes aegypti / Analysis / Brain / Dengue virus / Flavivirus / Infection / Newborn infants / Notes from the Field / Virus diseases / Zika virus

2016

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Evidence of Zika Virus Infection in Brain and Placental Tissues from Two Congenitally Infected Newborns and Two Fetal Losses — Brazil, 2015

in Aedes aegypti / Analysis / Brain / Dengue virus / Flavivirus / Infection / Newborn infants / Notes from the Field / Virus diseases / Zika virus

2016

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Journal Article

Evidence of Zika Virus Infection in Brain and Placental Tissues from Two Congenitally Infected Newborns and Two Fetal Losses — Brazil, 2015

de Oliveira Ramos, Ana Maria,

de Oliveria, Wanderson Kleber,

Goldsmith, Cynthia,

Luz, Kleber G.,

Bhatnagar, Julu,

Keating, M. Kelly,

Martines, Roosecelis Brasil,

Ritter, Jana,

Rollin, Dominique,

Muehlenbachs, Atis,

Gary, Joy,

Davi, Helaine Pompeia Freire,

Silva-Flannery, Luciana,

Lambert, Amy,

Hale, Gillian,

Shieh, Wun-Ju,

Zaki, Sherif,

Lanciotti, Robert

2016

Overview

Zika virus is a mosquito-borne flavivirus that is related to dengue virus and transmitted primarily by Aedes aegypti mosquitoes, with humans acting as the principal amplifying host during outbreaks. Zika virus was first reported in Brazil in May 2015. Here, Martines et al describe evidence of a link between Zika virus infection and microcephaly and fetal demise through detection of viral RNA and antigens in brain tissues from two congenitally infected newborns and two fetal losses reported in the country in 2015.

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Publisher

Center for Surveillance, Epidemiology, and Laboratory Services, Centers for Disease Control and Prevention (CDC), U.S. Department of Health and Human Services,U.S. Government Printing Office

Subject

/ Brain

/ Notes from the Field

/ Virus diseases

/ Zika virus