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The Role of sup.18FFES PET/CT in Breast Cancer Management: An Umbrella Review
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The Role of sup.18FFES PET/CT in Breast Cancer Management: An Umbrella Review
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Journal Article
The Role of sup.18FFES PET/CT in Breast Cancer Management: An Umbrella Review
2025
Overview
Breast cancer is the world’s most commonly diagnosed cancer and the leading cause of cancer-related death in women. Estrogen receptor (ER) status in tumors plays a key role in determining the treatment for breast cancer. However, assessing ER status can be challenging due to tumor heterogeneity and the limitations of current methods, including tissue biopsies and immunohistochemistry (IHC). This review focuses on the use of [[sup.18]F]FES PET/CT, an imaging method that provides an evaluation of ER activity across the body, potentially offering a non-invasive diagnosis. The aim of this study is to assess how [[sup.18]F]FES PET/CT can improve breast cancer diagnosis and treatment planning, particularly when biopsies are unfeasible or unsafe. The findings could help optimize therapy choices and lead to better management of breast cancer, particularly in cases of recurrence or metastasis.
Publisher
MDPI AG
Subject
