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Use of the Novel Therapeutic Agent Miltefosine for the Treatment of Primary Amebic Meningoencephalitis: Report of 1 Fatal and 1 Surviving Case
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Use of the Novel Therapeutic Agent Miltefosine for the Treatment of Primary Amebic Meningoencephalitis: Report of 1 Fatal and 1 Surviving Case
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Use of the Novel Therapeutic Agent Miltefosine for the Treatment of Primary Amebic Meningoencephalitis: Report of 1 Fatal and 1 Surviving Case
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Journal Article
Use of the Novel Therapeutic Agent Miltefosine for the Treatment of Primary Amebic Meningoencephalitis: Report of 1 Fatal and 1 Surviving Case
2016
Overview
Primary amebic meningoencephalitis (PAM) is a fulminant central nervous system infection caused by the thermophilic free-living ameba Naegleria fowleri. Few survivals have been documented and adequate treatment is lacking. We report 2 PAM cases, 1 fatal and 1 surviving, treated with the novel antiparasitic agent miltefosine.
Publisher
Oxford University Press
Subject
/ Antiprotozoal Agents - adverse effects
/ Antiprotozoal Agents - therapeutic use
/ Central Nervous System Protozoal Infections - diagnostic imaging
/ Central Nervous System Protozoal Infections - drug therapy
/ Central Nervous System Protozoal Infections - mortality
/ Central Nervous System Protozoal Infections - parasitology
/ Child
/ Humans
/ Male
/ Naegleria fowleri - drug effects
/ Naegleria fowleri - isolation & purification
/ Phosphorylcholine - adverse effects
/ Phosphorylcholine - analogs & derivatives
