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An MRI Atlas of the Human Fetal Brain: Reference and Segmentation Tools for Fetal Brain MRI Analysis
by
Wang, Jian
, Khan, Shadab
, Afacan, Onur
, Rollins, Caitlin K
, Ouaalam, Abdelhakim
, Jaimes, Camilo
, Velasco-Annis, Clemente
, Gholipour, Ali
, Calixto, Camilo
, Bagheri, Mahdi
, Faghihpirayesh, Razieh
, Warfield, Simon K
, Vasung, Lana
2025
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An MRI Atlas of the Human Fetal Brain: Reference and Segmentation Tools for Fetal Brain MRI Analysis
by
Wang, Jian
, Khan, Shadab
, Afacan, Onur
, Rollins, Caitlin K
, Ouaalam, Abdelhakim
, Jaimes, Camilo
, Velasco-Annis, Clemente
, Gholipour, Ali
, Calixto, Camilo
, Bagheri, Mahdi
, Faghihpirayesh, Razieh
, Warfield, Simon K
, Vasung, Lana
in
2025
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Do you wish to request the book?
An MRI Atlas of the Human Fetal Brain: Reference and Segmentation Tools for Fetal Brain MRI Analysis
by
Wang, Jian
, Khan, Shadab
, Afacan, Onur
, Rollins, Caitlin K
, Ouaalam, Abdelhakim
, Jaimes, Camilo
, Velasco-Annis, Clemente
, Gholipour, Ali
, Calixto, Camilo
, Bagheri, Mahdi
, Faghihpirayesh, Razieh
, Warfield, Simon K
, Vasung, Lana
2025
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An MRI Atlas of the Human Fetal Brain: Reference and Segmentation Tools for Fetal Brain MRI Analysis
Journal Article
An MRI Atlas of the Human Fetal Brain: Reference and Segmentation Tools for Fetal Brain MRI Analysis
2025
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Overview
Accurate characterization of in-utero brain development is essential for understanding typical and atypical neurodevelopment. Building upon previous efforts to construct spatiotemporal fetal brain MRI atlases, we present the CRL-2025 fetal brain atlas, which is a spatiotemporal (4D) atlas of the developing fetal brain between 21 and 37 gestational weeks. This atlas is constructed from carefully processed MRI scans of 160 fetuses with typically-developing brains using a diffeomorphic deformable registration framework integrated with kernel regression on age. CRL-2025 uniquely includes detailed tissue segmentations, transient white matter compartments, and parcellation into 126 anatomical regions. This atlas offers significantly enhanced anatomical details over the CRL-2017 atlas, and is released along with the CRL diffusion MRI atlas with its newly created tissue segmentation and labels as well as deep learning-based multiclass segmentation models for fine-grained fetal brain MRI segmentation. The CRL-2025 atlas and its associated tools provide a robust and scalable platform for fetal brain MRI segmentation, groupwise analysis, and early neurodevelopmental research, and these materials are publicly released to support the broader research community.
Publisher
Cornell University
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