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On the Evolution of Development
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Book Chapter
On the Evolution of Development
2017
Overview
This chapter takes the dogma of development and shows how it becomes part of the continuum of evolution using the provided principles. Calcium homeostasis counterbalanced by lipid homeostasis seems to underlie all of cellular evolution. All of the features of parathyroid hormone‐related protein (PTHrP) biology justify its use as an archetype for the proposed model of lung evolution. One of the predictions of the cellular‐molecular integrated approach to evolution is the primacy of the unicellular state as the founding and ongoing mechanism of evolution. By using the cellular‐molecular ontogenetic and phylogenetic approach described in the chapter for the water‐land transition as a major impetus for evolution, a similar approach can be used moving both forward and backward developmentally and phylogenetically from that critically important phase of vertebrate evolution. This approach will yield a priori knowledge about the first principles of physiology, and how they have evolved to generate form and function from their unicellular origins.
Publisher
John Wiley & Sons, Incorporated,John Wiley & Sons, Inc
Subject
ISBN
9781118729267, 1118729269
