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Cerebral small vessel disease: neuroimaging markers and clinical implication

by Chen, Xiaodong , Huang, Xuehong , Zhang, Bingjun , Lu, Zhengqi , Shan, Yilong , Liao, Siyuan , Hu, Mengyan , Wang, Jihui , Wang, Yuge , Liu, Sanxin , Cai, Wei

in Arterioles / Capillaries / Cerebrovascular diseases / Cognitive ability / Medical imaging / Mental disorders / Neuroimaging / Neurology / Pathogenesis / Substantia alba / Vascular diseases

2019

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Cerebral small vessel disease: neuroimaging markers and clinical implication

by Chen, Xiaodong , Huang, Xuehong , Zhang, Bingjun , Lu, Zhengqi , Shan, Yilong , Liao, Siyuan , Hu, Mengyan , Wang, Jihui , Wang, Yuge , Liu, Sanxin , Cai, Wei

in Arterioles / Capillaries / Cerebrovascular diseases / Cognitive ability / Medical imaging / Mental disorders / Neuroimaging / Neurology / Pathogenesis / Substantia alba / Vascular diseases

2019

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Cerebral small vessel disease: neuroimaging markers and clinical implication

by Chen, Xiaodong , Huang, Xuehong , Zhang, Bingjun , Lu, Zhengqi , Shan, Yilong , Liao, Siyuan , Hu, Mengyan , Wang, Jihui , Wang, Yuge , Liu, Sanxin , Cai, Wei

in Arterioles / Capillaries / Cerebrovascular diseases / Cognitive ability / Medical imaging / Mental disorders / Neuroimaging / Neurology / Pathogenesis / Substantia alba / Vascular diseases

2019

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Journal Article

Cerebral small vessel disease: neuroimaging markers and clinical implication

Chen, Xiaodong,

Huang, Xuehong,

Zhang, Bingjun,

Lu, Zhengqi,

Shan, Yilong,

Liao, Siyuan,

Hu, Mengyan,

Wang, Jihui,

Wang, Yuge,

Liu, Sanxin,

Cai, Wei

2019

Overview

Cerebral small vessel disease (CSVD) is a broad category of cerebrovascular diseases which primarily affect the perforating arterioles, capillaries and venules with multiple distinct etiologies. In spite of distinctive pathogenesis, CSVD shares similar neuroimaging markers, including recent small subcortical infarct, lacune of presumed vascular origin, white matter hyperintensity of presumed vascular origin, perivascular space and cerebral microbleeds. The radiological features of neuroimaging markers are indicative for etiological analysis. Furthermore, in sporadic arteriosclerotic pathogenesis associated CSVD, the total CSVD burden is a significant predictor for stroke events, global cognitive impairment, psychiatric disorders and later life quality. This review aims to summarize the radiological characteristics as well as the clinical implication of CSVD markers and neuroimaging interpretation for CSVD symptomatology.

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Publisher

Springer Nature B.V

Subject

Arterioles

/ Capillaries

/ Cerebrovascular diseases