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Cognitive rehabilitation for executive dysfunction in brain tumor patients: a pilot randomized controlled trial
by
Berlin, Alejandro
, Mason, Warren P.
, Millar, Barbara-Ann
, Edelstein, Kim
, Laperriere, Normand
, Shultz, David B.
, Richard, Nadine M.
, Maurice, Catherine
, Bernstein, Lori J.
in
Brain cancer
/ Brain health
/ Brain tumors
/ Clinical Study
/ Clinical trials
/ Cognitive ability
/ Executive function
/ Medicine
/ Medicine & Public Health
/ NCT
/ NCT02489071
/ Neurology
/ Oncology
/ Quality of life
/ Rehabilitation
2019
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Cognitive rehabilitation for executive dysfunction in brain tumor patients: a pilot randomized controlled trial
by
Berlin, Alejandro
, Mason, Warren P.
, Millar, Barbara-Ann
, Edelstein, Kim
, Laperriere, Normand
, Shultz, David B.
, Richard, Nadine M.
, Maurice, Catherine
, Bernstein, Lori J.
in
Brain cancer
/ Brain health
/ Brain tumors
/ Clinical Study
/ Clinical trials
/ Cognitive ability
/ Executive function
/ Medicine
/ Medicine & Public Health
/ NCT
/ NCT02489071
/ Neurology
/ Oncology
/ Quality of life
/ Rehabilitation
2019
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Do you wish to request the book?
Cognitive rehabilitation for executive dysfunction in brain tumor patients: a pilot randomized controlled trial
by
Berlin, Alejandro
, Mason, Warren P.
, Millar, Barbara-Ann
, Edelstein, Kim
, Laperriere, Normand
, Shultz, David B.
, Richard, Nadine M.
, Maurice, Catherine
, Bernstein, Lori J.
in
Brain cancer
/ Brain health
/ Brain tumors
/ Clinical Study
/ Clinical trials
/ Cognitive ability
/ Executive function
/ Medicine
/ Medicine & Public Health
/ NCT
/ NCT02489071
/ Neurology
/ Oncology
/ Quality of life
/ Rehabilitation
2019
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Cognitive rehabilitation for executive dysfunction in brain tumor patients: a pilot randomized controlled trial
Journal Article
Cognitive rehabilitation for executive dysfunction in brain tumor patients: a pilot randomized controlled trial
2019
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Overview
Purpose
Patients with brain tumors face unique quality of life challenges. Executive dysfunction is common and functionally limiting, with no established treatments as standard care. This pilot study evaluated the efficacy of Goal Management Training (GMT), a behavioral intervention combining mindfulness and strategy training, for improving executive and real-life functioning in this population.
Methods
Twenty-five primary brain tumor survivors were randomized to GMT, an active control (Brain Health Program, BHP), or a wait-list (WAIT) control group. The BHP was a supportive care intervention offering education and activities to promote general brain health, without cognitive strategy training. Participants in GMT and BHP completed eight individual sessions and homework between sessions; those in WAIT received usual care. Assessments at baseline, immediately post-training, and 4-month follow-up used a battery of objective and subjective measures, including functional goal attainment.
Results
Adherence (% sessions completed) was high for both GMT (98.9%) and BHP (84.4%). Executive functions improved with GMT but not BHP or WAIT (repeated measures analysis of variance, time-by-group interaction, post-training
P
= 0.077, follow-up
P
= 0.046). Both intervention groups reported fewer cognitive concerns at post-training (
P
= 0.049) and follow-up (
P
< 0.001). Functional goal attainment was greatest with GMT (post-training
P
= 0.027, follow-up
P
= 0.064).
Conclusions
GMT improved executive and real-life functioning in brain tumor survivors, with gains maintained at 4-month follow-up. Clinical implementation of this adaptable program merits consideration for clinically stable patients with cognitive dysfunction. Further development and larger prospective cognitive rehabilitation trials appear warranted.
Publisher
Springer US,Springer Nature B.V
Subject
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