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Reaction Phenotyping
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Book Chapter
Reaction Phenotyping
2012
Overview
This chapter contains sections titled:
Introduction
Initial Considerations
CYP Reaction Phenotyping
Non‐P450 Reaction Phenotyping
UGT Conjugation Reaction Phenotyping
Reaction Phenotyping for Other Conjugation Reactions
Integration of Reaction Phenotyping and Prediction of DDI
Conclusion
References
Publisher
John Wiley & Sons, Inc
Subject
CYP reaction phenotyping, chemical inhibitors of CYP isoforms
/ in vitro phenotyping, for drug metabolizing enzymes in drug discovery
/ individual drug metabolizing enzymes, clearance of drug candidate
/ reaction phenotyping for other conjugation reactions
/ reaction phenotyping or isozyme mapping, and NCE metabolism
ISBN
0470542780, 9780470542781
