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The Genome, Genes and Brain – Tailored Drugs
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Book Chapter
The Genome, Genes and Brain – Tailored Drugs
2010
Overview
This chapter contains sections titled:
Introduction
Issues in new drug development
Early development of psychiatric pharmaceutical entities
Advances in research technology
Review of genetics
Activation of genes by signal transduction cascades
The human genome
The sequencing of the genome
DNA variation
Genes and illness
Genomic findings, potential targets and new drug development
Conclusion
Publisher
John Wiley & Sons, Ltd
Subject
development of psychiatric pharmaceutical entities
/ duration and cost of drug development and approval process
/ four major signal cascade pathways ‐ activating nuclear transcription factors
/ genome, genes and brain – tailored drugs
/ Human Genome Project, completed sequencing human genome in 2003
/ major psychiatric illnesses and complex polygenic disorders
/ potential gene therapies in preventing major psychiatric disorders
ISBN
0470740760, 9780470740767
