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Anthocyanins in metabolic health and disease
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Anthocyanins in metabolic health and disease
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Anthocyanins in metabolic health and disease
Anthocyanins in metabolic health and disease
Book Chapter

Anthocyanins in metabolic health and disease

2017
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Overview
This chapter presents recent evidence to demonstrate that different anthocyanin (ANC) aglycones can differ markedly in terms of bioavailability, absorption, metabolism, metabolic breakdown products, and excretion to produce wide‐ranging impacts on human metabolic health and disease. In more recent years, stable isotope labeling has provided new insights into the complex issue of ANCs disposition after ingestion. ANC deposition in various tissues has been studied in animal models. Several studies have demonstrated that detectable levels of ANCs occur in brain tissue after ingestion. Modern nutritional supplementation with ANCs aimed at metabolic health promotion and disease risk reduction revealed several nutrigenomic biomarkers that might explain how an anthocyanin‐rich diet influences gene transcription, protein expression, and metabolism. Taken together, these new findings provide a strong scientific basis for developing new anthocyanin‐rich foods, cultivars of existing crops, and dietary supplements adapted to the specific needs of consumers and targeted to a specific group of metabolic risk factors.