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Role of Finger Prick Platelet Aggregation Test and Clot Retraction
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Role of Finger Prick Platelet Aggregation Test and Clot Retraction
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Journal Article
Role of Finger Prick Platelet Aggregation Test and Clot Retraction
2021
Overview
Objective Congenital platelet dysfunction is a rare disease with significant morbidity and mortality. No studies to characterize this group of disorders were done in Sudan.. This is the only center in Sudan looking after patients with bleeding disorders including those with platelet dysfunction.. Because there is no facilities for specific test, the lab of Haemophilia center depend on Finger Prick Platelet Aggregation test in the diagnosis of this disorder.So the main objective of this study is to compare between clot retraction test and finger prick platelet aggregation test and the role of each test in the diagnosis of this disorders. Methods: This was a prospective case control study. This study was done in Haemophilia Center and underling laboratory in Khartoum Teaching Hospital. In the period between March 2013 to February 2017. Clot retraction test and finger prick platelet aggregation test were done for 30 patients with congenital platelet dysfunction and 30 normal subjects.. Results: The clot retraction test and finger prick platelet aggregation test, 30 normal subjects had normal clot retraction and normal finger prick platelet aggregation. Clot retraction was poor in 29 patients and normal in one patient. Finger prick platelet aggregation test was normal in 3 patients and poor in 27 patients. Conclusions: Finger prick platelet aggregation test detect and diagnose most of the patients with this disorder when the specific test is expensive or not available. It is sensitive test but not specific, cannot determine the type of congenital platelet dysfunction. Clot retraction test support the diagnosis of disease but cannot depend on it. This test can be used in combination with finger prick platelet aggregation test in the absence of facilities for specific tests.
Publisher
جامعة دنقلا - كلية الدراسات العليا
Subject
