Asset Details
Do you wish to reserve the book?
Study the Potential Protective Effect of Ethanolic Extract of Coriander \Coriandrum Sativum\ Leaves and Seeds against Lead Toxicity in Rats
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Study the Potential Protective Effect of Ethanolic Extract of Coriander \Coriandrum Sativum\ Leaves and Seeds against Lead Toxicity in Rats
Do you wish to request the book?
Study the Potential Protective Effect of Ethanolic Extract of Coriander \Coriandrum Sativum\ Leaves and Seeds against Lead Toxicity in Rats
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Study the Potential Protective Effect of Ethanolic Extract of Coriander \Coriandrum Sativum\ Leaves and Seeds against Lead Toxicity in Rats
2023
Overview
Bioactive compounds found in natural sources have the potential to act as oxygen free cleaners or metal chelators, enabling their use as natural antidote for heavy metal toxicity. So, in this research , the ethanolic extract of Coriandrum sativum leaves and seeds was evaluated for its potential effect in reducing the harmful effect of lead in rats. Thirty rats were randomly divided into 6 groups. Group1 set as a negative control group. Group 2 received a daily dose of lead acetate (40 mg/kg body weight orally) for 7 days for induction of oxidative stress then reclassified into 5 groups . Group 2 was left as a positive control group .Group three and four received an oral dose of coriander leaves extract (100 and 200 mg /kg), respectively. While the fifth and sixth group received an oral dose of coriander seeds extract (100 and 200 mg /kg), respectively. The content of coriander leaf and seed extracts of phenolic and flavonoid substances was estimated. Also, the effect of these treatments on lead concentration in serum, liver and brain, kidney and liver function markers, lipid profile, oxidative stress markers, glucose level , and histopathological changes in liver and brain was evaluated .The results showed an increase in indicators of liver and kidney function ,lipid profile, glucose level and in the signs of oxidative stress in rats treated with lead acetate ,while the effect was mitigated by leaf and seed coriander extract. Also, extract improved the tissue structure of the liver and brain. The effect of coriander leaves was more pronounced than that of the seeds. From the previous results it was shown that coriander possesses antioxidant activity and thus can be used as a natural chelating agent for lead toxicity.
Publisher
جامعة المنيا - كلية التربية النوعية
Subject
