Journal Article

The Protective Effect of Ginkgo Biloba Leaves and Cassia Tora Seeds on Hyper cholesterolemic Rats

Adyia, Merna El-Sayed, Abdel Majid, Ashraf Abdel Aziz, Najm, Shaima Hassan

2023

Overview

This study looked at how Ginkgo biloba leaves (GB) and Cassia tora seeds affected hypercholesterolemic rats lipid profiles for eight weeks. Thirty six adult male rats were divided into two main groups. The first main group (six rats) were fed a regular diet and used (- ve control group). The second main group of 30 rats, fed on a high- cholesterol diet to induce hypercholesterolemia for 7 weeks, then was divided into five subgroups as follows: Subgroup (1) was fed a high- cholesterol diet and used as a positive control group. Subgroup (2 and 3) were given high- cholesterol diets that included supplements of 5% and 10% Gb leaves powder, respectively. Subgroup (4 and 5) were given high- cholesterol diets that included supplements of 5% and 10% powder from C. tora seeds, respectively. According to the obtained findings, liver enzymes, kidney functions and lipid profile were found to be significantly decreased (P≤0.05) while, HDL- C was noticeably increased by Gb leaves or C. tora seeds at the tested levels as compared to the positive control group. Furthermore, significantly increased in antioxidant enzymes (SOD and CAT) while, a decrease in MDA by Gb leaves or C. tora seeds supplementation at the tested levels in hypercholesterolemic rats. In conclusion that Gb leaves or C. tora seeds significantly reduced cholesterol levels while also improved liver enzymes, kidney functions and antioxidant enzyme. Therefore, Gb leaves or C. tora seeds may be recommended for hypercholesterolemic patients.

• Publisher: جامعة بورسعيد - كلية التربية النوعية
• Subject: ارتفاع الكوليسترول / العلاج بالأعشاب / النظام الغذائي / مستويات الدهون / وظائف الكلى