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An outbreak of dengue fever in Peri Urban slums of Chandigarh, India, with special reference to entomological and climatic factors
by
Ratho RK, Mishra B, Kaur J, Kakkar N, Sharma K
in
Dengue, epidemic, India, Reverse transcription-polymerase chain reaction
2006
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An outbreak of dengue fever in Peri Urban slums of Chandigarh, India, with special reference to entomological and climatic factors
by
Ratho RK, Mishra B, Kaur J, Kakkar N, Sharma K
in
Dengue, epidemic, India, Reverse transcription-polymerase chain reaction
2006
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An outbreak of dengue fever in Peri Urban slums of Chandigarh, India, with special reference to entomological and climatic factors
Journal Article
An outbreak of dengue fever in Peri Urban slums of Chandigarh, India, with special reference to entomological and climatic factors
2006
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Overview
Backgrounds: Dengue viral infection is one of the most important
public health problem in tropical countries. Aim: An outbreak of dengue
fever was investigated in a periurban slum area of Chandigarh, India,
during September to December, 2002. Materials and methods: Blood
samples from 218 patients and 30 apparently healthy contacts were
tested for dengue-specific immunoglobulin M (IgM) and IgG antibodies
including 80 acute samples collected within 5 days of illness were
subjected for virus isolation in newborn mice. The average temperature,
rainfall, and humidity of the epidemic year were compared with the
number of dengue cases. Statistical analysis: statistical significance
was found out using β2-test. Results: A total of 76 cases were
positive by either dengue IgM capture assay (n=57) or virus isolation
(n=17) or both (n=2). fifteen of nineteen viral isolates subjected for
typing by type-specific multiplex reverse transcription-polymerase
chain reaction were found to be of dengue virus. High rainfall and
humidity with the temperature range from 21°c to 33°c during
the months of August and September might have favored the breeding of
mosquitoes, thus leading to an increase in the number of dengue cases
in October and November, 2002. Conclusion: The present outbreak thus
emphasizes the need for continuous sero epidemiological and
entomological surveillance for the timely implementation of effective
dengue control programme.
Publisher
Medknow Publications on behalf of Indian Journal of Medical Sciences Trust
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