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(18)F-FDG PET/CT显像中肺外病变对肺癌的辅助定性诊断价值
by
米宝明 万卫星 郁春景 尤徐阳 蒋峰 游庆军
in
X线计算机断层术
/ 体层摄影术
/ 发射型计算机
/ 肺肿瘤
/ 诊断
2012
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(18)F-FDG PET/CT显像中肺外病变对肺癌的辅助定性诊断价值
by
米宝明 万卫星 郁春景 尤徐阳 蒋峰 游庆军
in
X线计算机断层术
/ 体层摄影术
/ 发射型计算机
/ 肺肿瘤
/ 诊断
2012
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Journal Article
(18)F-FDG PET/CT显像中肺外病变对肺癌的辅助定性诊断价值
2012
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Overview
背景与目的 ^(18)F-脱氧葡萄糖(fluorodeoxyglucose,FDG)正电子发射体层摄影术/计算机体层摄影术(positron emission tomography/computed tomography,PET/CT)对肺癌和部分肺良性病变的鉴别诊断仍有一定困难,本研究旨在探讨PET/CT显像中肺外病变对肺癌的辅助定性诊断价值。方法回顾性分析126例行PET/CT检查的疑诊肺癌病例。初始诊断仅根据肺内病变的PET表现、平均标准摄取值(mean standardized uptake value,SUVmean)和CT征象,然后根据肺外病变情况对肺内病变的诊断进行修正,比较修正前后诊断结果有无差异。结果 PET/CT发现81例同时伴有肺外病变,肺外转移性病变使13例可疑恶性修正为肯定恶性,1例良性修正为肯定恶性;肺外非转移性病变使2例可疑恶性修正为肯定恶性,1例可疑恶性修正为良性。除2例全身结核被错误修正为恶性外,其它15例经病理证实均为正确修正。修正前后PET/CT的诊断结果差异有统计学意义,修正诊断率为13.5%(17/126),修正诊断正确率为88.2%(15/17)。结论肺外病变的发现对肺癌的术前定性有着较好的实用价值,提高了诊断效能,但仍然要注意与全身多发结核等炎性病变鉴别。
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