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2型糖尿病患者经皮氧分压与神经传导功能测定的相关性分析
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2型糖尿病患者经皮氧分压与神经传导功能测定的相关性分析
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Journal Article
2型糖尿病患者经皮氧分压与神经传导功能测定的相关性分析
2013
Overview
目的探讨2型糖尿病患者经皮氧分压（TcPO2）与神经传导功能测定（NCS）结果的相关性。方法收集第三军医大学西南医院2012年1-7月年龄匹配的2型糖尿病住院患者381例,根据NCS是否异常以及有无糖尿病周围神经病变（DPN）症状分为4组：1组（有NCS异常,无DPN症状）129例、2组（无NCS异常,有DPN症状）50例、3组（有NCS异常,有DPN症状）122例、4组（无NCS异常,无DPN症状）80例,其中1、3组为DPN组,2组为疑似DPN组,4组为无DPN组。分析TcPO2立位、卧位、立卧位差值等33项指标的组间差异以及TcPO2与NCS各参数的相关性。结果与无DPN组比较,DPN组、疑似DPN组TcPO2立位、卧位值降低,立卧位差值增高（P〈0.05）。TcPO2立位值与NCS的正中神经运动传导速度、远端潜伏期、复合肌肉动作电位波幅等26项参数均相关（P〈0.05）,TcPO2卧位值与除F波最短潜伏期以外的25项参数相关,TcPO2立卧位差值则与其中11项参数相关（P〈0.05）。结论 TcPO2与NCS有很好的相关性,有望成为DPN的有效检测手段。
