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低熔点铅在Graves眼病放疗中的剂量学优势分析
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低熔点铅在Graves眼病放疗中的剂量学优势分析
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Journal Article
低熔点铅在Graves眼病放疗中的剂量学优势分析
2013
Overview
目的对低熔点铅（LML）和多叶光栅（MLc）两种照射野成形方法在眼眶放疗中的剂量学差异进行比较，以便使用晶体剂量更低的技术用于临床Graves眼病的治疗。方法选择适于放疗的单、双侧Graves眼病患者各10例，采用相同的靶区勾画原则，计划靶区（PTv）处方剂量为2000cGy／10次，单侧组布野方法为3野（2个X线平野＋1个电子线野），双侧组为4野（2个X线平野＋2个电子线野），分别采用LML和MLC形成照射野。比较两种照射野成形方法的靶区适形指数（cI）和剂量体积直方图（DVH）；采用免冲洗胶片和剂量分析软件分析两种方法形成半野照射野的有效半影区大小及其对晶体受量的影响。结果MLC单侧组患侧晶体剂量为582±34cGy，健侧晶体剂量为160±22cGy，CI为0．69；双侧组左右晶体剂量分别为591±47cGy和585±52cGy，CI为0．67。LML单侧组患侧晶体剂量为252±45cGy，健侧晶体剂量为148±19cGy，CI为0．71；双侧组左右晶体剂量分7~112474-44、256±42cGy，CI为0．68。在X线能量设定为4MV和8MV时，半野照射野5cm×5cm，深度4cm，LML的有效半影区与MLC比较小约3mm。结论用LML来形成小面积照射野可能更加适形，并可减小照射野半影，显著降低患者患侧晶体的受量。
