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GOTcha： IncRNA-ACOD1 targets metabolism during viral infection
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Journal Article
GOTcha： IncRNA-ACOD1 targets metabolism during viral infection
2018
Overview
Long-noncoding RNAs （lncRNAs） are emerging as important regulators of cellular processes, but few have been functionally characterized in host-pathogen interactions. A recent report in Science demonstrates a mechanistic role for a novel lncRNAin directly binding an essential metabolic enzyme, glutamic-oxaloacetic trans- aminase （GOT2）; this interaction benefits viral replication via alteration of host metabolism.
Subject
