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Hemocultura: técnica sensível na detecção do Trypanosoma cruzi em pacientes chagásicos na fase crônica da doença de Chagas Hemoculture: a sensitive technique for detecting Trypanosoma cruzi in patients in the chronic phase of Chagas' disease
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Hemocultura: técnica sensível na detecção do Trypanosoma cruzi em pacientes chagásicos na fase crônica da doença de Chagas Hemoculture: a sensitive technique for detecting Trypanosoma cruzi in patients in the chronic phase of Chagas' disease
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Hemocultura: técnica sensível na detecção do Trypanosoma cruzi em pacientes chagásicos na fase crônica da doença de Chagas Hemoculture: a sensitive technique for detecting Trypanosoma cruzi in patients in the chronic phase of Chagas' disease
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Journal Article
Hemocultura: técnica sensível na detecção do Trypanosoma cruzi em pacientes chagásicos na fase crônica da doença de Chagas Hemoculture: a sensitive technique for detecting Trypanosoma cruzi in patients in the chronic phase of Chagas' disease
1994
Overview
A sensibilidade de hemoculturas, realizadas uma ou três vezes, foi estudada em 52 pacientes na fase crônica da doença de Chagas. Modificações foram introduzidas na técnica tais como, diminuição do período de processamento do sangue, homogeneização suave e exame até 120 dias do cultivo. Os resultados mostram alto percentual de positividade, ou seja, 79% e 94% dos pacientes foram positivos, respectivamente, com um ou três testes. A julgar pela número de tubos positivos, em cada paciente, a parasitemia foi baixa em 59% deles, média em 16% e alta em 25%. Não houve diferenças significativas nos resultados positivos em função da idade dos pacientes, que variou de 14 a 82 anos. Nossos resultados demonstram que a hemocultura é uma metodologia sensível para o diagnóstico parasitológico da doença de Chagas e ideal para monitorar cura em pacientes submetidos a tratamento.The sensitivity ofhemocultures, performed once or three times, was investigated in 52 patients in the chronic phase of Chagas disease. Modifications were introduced in the technique such as, processing the blood more rapidly, gently homogenizing the cultures and examining them after 120 days of culture. Our results show a high percent age of positivity i.e. 79% and 94% of patients submitted, respectively, to one or three tests. No significant differences related to the patients age were detected, which varied from 14 to 82 years old. Our results demonstrate that hemoculture is a sensitive method for the parasitological diagnosis of Chagas disease and is ideal for monitoring cure in treated patients.
Publisher
Sociedade Brasileira de Medicina Tropical (SBMT)
