Asset Details
Do you wish to reserve the book?
Vitamin d status of children with moderate to severe chronic kidney disease at a tertiary pediatric center in cape town
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Vitamin d status of children with moderate to severe chronic kidney disease at a tertiary pediatric center in cape town
Do you wish to request the book?
Vitamin d status of children with moderate to severe chronic kidney disease at a tertiary pediatric center in cape town
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Vitamin d status of children with moderate to severe chronic kidney disease at a tertiary pediatric center in cape town
2019
Overview
The prevalence of suboptimal Vitamin D levels is higher in patients with chronic
kidney disease (CKD) than in the general population. Recent findings suggest that progression of
CKD is linked to a suboptimal Vitamin D level. A high percentage of CKD patients have severe
Vitamin D deficiency. These patients also have a low level of 25-hydroxy-vitamin D [25(OH)D]
and consequently, a reduced ability to form active 1,25-dihydroxyvitamin D. Various factors
underlie the low level of 25(OH)D, including a sedentary lifestyle, decreased intake of Vitamin D
due to CKD-related dietary restrictions, and decreased synthesis of Vitamin D in skin due to
uremia. All these factors may be particularly influential in patients with progressively worsening
CKD, including those receiving chronic dialysis. The objective of our study is to determine the
prevalence of Vitamin D deficiency in children with CKD stages three to five and those receiving
chronic dialysis, to ascertain whether there is a relationship between Vitamin D deficiency and
the stage of CKD, and to identify any clinical correlates associated with the Vitamin D status. A
single-center, retrospective review was conducted of 46 children (younger than 18 years) with
CKD stages 3–5D who attended the renal clinic of the Red Cross Children’s Hospital between
October 2013 and November 2014. In total, 73.9% of the study population had suboptimal
Vitamin D levels (43.5% and 30.4% had Vitamin D deficiency and insufficiency, respectively).
The prevalence of Vitamin D deficiency was significantly higher in older children (≥10 years of
age) than in younger children (P = 0.000) but did not significantly differ between males and
females (P = 0.693). In total, 12 of 15 black children (80%), 19 of 26 colored children (73.1%),
two of four white children (50%), and one Asian child (100%) had suboptimal Vitamin D levels
Publisher
Saudi Center for Organ Transplantation
Subject
