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Phenolic Compounds from Cotinus Coggygria Scop. with Alpha Glucosidase Inhibition
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Phenolic Compounds from Cotinus Coggygria Scop. with Alpha Glucosidase Inhibition
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Journal Article
Phenolic Compounds from Cotinus Coggygria Scop. with Alpha Glucosidase Inhibition
2019
Overview
(Anacardiaceae) is used in Turkish folk medicine to treat DM. [...]the bioguided fractionation and isolation studies were carried on C. coggygria. The inhibition of the key enzymes in digestion of dietary starch such as a-amylase and a-glucosidase provides to control blood glucose level (Hamid et al., 2015). [...]of this study five phenolic compounds were isolated as well as the assessment of their a-glucosidase and a-amylase inhibition effects. The glucose core with one or more galloyl groups is necessary to interact with and stimulate the receptor target (Ren et al., 2006). [...]it should be stated that compound 2 was inactive against a-glucosidase because of lack of a sugar moiety.
Publisher
Hacettepe University Faculty of Medicine
Subject
