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FPIN's Help Desk Answers: Electronic Cigarettes for Smoking Cessation
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Journal Article
FPIN's Help Desk Answers: Electronic Cigarettes for Smoking Cessation
2016
Overview
A systematic review pooled two randomized controlled trials (RCTs) and found six-month quit rates of 9% for e-cigarettes compared with 4% for placebo (N = 662; relative risk [RR] = 2.29; 95% confidence interval [CI], 1.05 to 4.96).1 The number of participants who reported reducing their cigarette consumption by at least 50% was 36% in the nicotine-containing e-cigarette group compared with 27% in the placebo group (N = 612; RR = 1.31; 95% CI, 1.02 to 1.68). A double-blind RCT enrolled 300 healthy middle-aged adults (63% male) who smoked more than 10 cigarettes per day for at least five years and who did not desire to quit.3 Smoking cessation rates were compared between three groups: two received different doses of nicotine-containing e-cigarettes, and the third received a non-nicotine-containing e-cigarette. In 2015, it issued warning letters to three major e-cigarette companies for violations, including unsubstantiated claims and violating the Federal Food, Drug, and Cosmetic Act.4 Copyright Family Physicians Inquiries Network.
Publisher
American Academy of Family Physicians
Subject
