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慢性病毒性肝炎患者服用阿司匹林与肝细胞癌发生率及肝病相关死亡率的关系
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Journal Article
慢性病毒性肝炎患者服用阿司匹林与肝细胞癌发生率及肝病相关死亡率的关系
2020
Overview
<正>目前,慢性HBV、HCV感染人群服用小剂量阿司匹林 (≤160 mg) 是否对肝细胞癌发生率、肝病相关死亡率和胃肠道出血风险产生长期影响,尚需要更多研究数据来阐明。来自哈佛医学院马萨诸塞综合医院的Tracey等针对瑞典慢性病毒性肝炎患者进行了一项全国性研究,通过瑞典全国疾病登记系统统计2005年-2015年确诊为慢性乙型或丙型肝炎且无阿司匹林服药史的成年人,共计50 275例患者纳入研究。通过瑞典处方药登记系统进一步识别出携带处方首次在药房领取连续90 d或更长时间剂量阿司匹林的患者,将纳入人群分为服用小剂量阿司匹林组 (n=14 205) 和未服用组 (n=36 070) ,平均随访7. 9年。通过构建
Publisher
Journal of Clinical Hepatology
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