Journal Article

P055 Comparison of preoxygenation with a high-flow nasal cannula and a simple anatomical mask before intubation during induction of general anaesthesia in patients undergoing surgery for cervical spinal cord injury

Bais, Prateek Singh

2025

Overview

Please confirm that an ethics committee approval has been applied for or granted: Yes: I’m uploading the Ethics Committee Approval as a PDF file with this abstract submissionApplication for ESRA Abstract Prizes: I apply as an Anesthesiologist (Aged 35 years old or less)Background and AimsPreoxygenation is an important procedure which is necessary prior to induction of General Anesthesia (GA). It is achieved by administering oxygen using devices like face mask, nasal prongs etc and is characterised by increasing safe apnoea time. .By increasing safe apnoea time , we can prevent possible life threatening events which can occur during ventilation or intubation, during securing airway. Aim of Study: To evaluate and compare role of preoxygenation with HFNC vs preoxygenation with facemask in improving oxygenation and decreasing episodes of desaturation during induction in cervical cord injury patients.MethodsWe designed a prospective observational study and got it approved from institutional ethical committee ((IEC:2022–104-IMP-128, PGI/BE/512/2022). .For both the groups baseline ABGA (T0), ABG after preoxygenation ABGA (T1) and ABG after confirming intubation ABG (T2) was done.PaO2 trajectory through the procedure including apnea time was recorded. Statistical testing was performed for Patient data and ABG results using Wilcoxon test, Man-Whitney-U test and Chi-square test and Statistical significance level was assumed for p value lower than 0.05.ResultsThe basal characteristics showed no difference between the two groups. The mean apnoea times showed no significant difference between the two groups, 156.4±44.0 seconds and 151.2±61.3 seconds, in mask and HFNC groups, respectively (P=0.732). The longest safe apnea time was 412 seconds in the HFNC group. PaO2 at T2, which was the primary outcome of this study, showed a statistically significant difference. PaO2 at T2 of the HFNC group was higher, 454.2 mm Hg (95% confidence interval [CI], 414.1–489.52 mm Hg), while that of the mask group was 369.6 mm Hg (95% CI, 329.7–404.5 mm Hg) (P=0.002).ConclusionsIn this prospective randomized controlled study, preoxygenation using the HFNC showed higher PaO2 immediately after intubation compared to the conventional method with a simple face mask.

• Publisher: BMJ Publishing Group LTD
• Subject: Intubation