Asset Details
Do you wish to reserve the book?
P231 Effect of dexamethasone addition to ropivacaine on post-operative analgesia after percutaneous nephrolithotomy: a prospective randomized controlled trial
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
P231 Effect of dexamethasone addition to ropivacaine on post-operative analgesia after percutaneous nephrolithotomy: a prospective randomized controlled trial
Do you wish to request the book?
P231 Effect of dexamethasone addition to ropivacaine on post-operative analgesia after percutaneous nephrolithotomy: a prospective randomized controlled trial
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
P231 Effect of dexamethasone addition to ropivacaine on post-operative analgesia after percutaneous nephrolithotomy: a prospective randomized controlled trial
2025
Overview
Please confirm that an ethics committee approval has been applied for or granted: Yes: I’m uploading the Ethics Committee Approval as a PDF file with this abstract submission Application for ESRA Abstract Prizes: I apply as an Anesthesiologist (Aged 35 years old or less)Background and AimsBackground: Percutaneous nephrolithotomy and placement of nephrostomy tube is performed for renal stones > 2 cm in diameter. Attempts have been made to infiltrate local anaesthetics with or without adjuvants into the surgical site to reduce pain. We hypothesized that there would be a significant prolongation of the analgesic effect of local anaesthetic instillation along nephrostomy tube due to the adjuvant dexamethasone. Aims/Objectives: We compared the duration of analgesia in terms of the maximum numeric rating scale at 2,4,6,12,24, 48 and 60 hours postoperatively between Ropivacaine (R) and Ropivacaine-dexamethasone (R+D) groups. The total cumulative dose of Ropivacaine and Dexamethasone and the rescue analgesic fentanyl along with ESR and CRP were also determined.MethodsAfter ethical approval and CTRI registration (CTRI/2020/03/024332), 64 ASA I&II adult patients were enrolled in this randomized double blinded prospective study divided into Group R – received 20 ml 0.2% Ropivacaine and Group R+D – received 20 ml 0.2% Ropivacaine with dexamethasone 8 mg, injected through a multi-lumen wound infiltration catheter.ResultsThe demographic profile of patients was similar in both the groups. The mean duration of analgesia was longer in Group R+D (21.3 +/- 2.1 hrs) vs Group R (10+/-1.9 hrs, p = 0.001). The mean NRS scores of Group R+D were significantly lower at all time intervals (p = 0.001). Also, the cumulative dose of ropivacaine and the total use of fentanyl postoperatively in group R was much higher (70+/-10.4 vs 56+/- 8.9 mcg, p = 0.02). The CRP levels were significantly lower in Group R+D (13.8 +/- 1.5 vs 23.1 +/- 1.2 mg/L, p=0.001 and 16.5 +/- 1.3 vs 28.5 +/- 1.7 mg/L, p=0.001, at 24 and 48 hours respectively).ConclusionsWe conclude that dexamethasone can be used as a suitable adjuvant to intermittent local anaesthetic infiltration after PCNL with nephrostomy tube for the prolongation of analgesia.
Publisher
BMJ Publishing Group LTD
Subject
