Journal Article

P255 Obstructive spirometry in a severe pectus excavatum cohort: data from the national pectus MDT

Wallace, G, Ricketts, W, Astin, R, Kolvekar, S, Dunning, J, Egan, S

2025

Overview

The National Pectus multi-disciplinary team (MDT) meeting was commissioned by NHS England in April 2023 to review all cases of pectus excavatum (PE) being considered for surgical management. In cases of severe PE, the chest wall compresses the heart and lungs, which may result in cardiac or respiratory function compromise on exercise, measured during cardio-pulmonary exercise testing (CPET). This MDT has led to a further ongoing study on the impact of the timing of surgery on patient-reported improvement in quality of life, and improvement in CPET parameters (the RESTORE trial).All patients discussed in the MDT require prior CPET and pulmonary function testing (PFT) to assess for physiological limitation and investigate for other potential causes. The majority of PE patients have restrictive spirometry, however a subset of 28 patients potentially had an obstructive spirometry pattern (table 1), with a mean FEV1/FVC 0.72. This population was predominantly male (85.7%) with an average age of 22.3 years.Prior to surgical intervention, we propose these patients undergo further investigation to exclude undiagnosed obstructive airways disease, and in event of a diagnosis being made, receive a trial of treatment which may alleviate the need for an invasive surgical procedure.Abstract P255 Table 1Demographics (N=28)

• Publisher: BMJ Publishing Group LTD
• Subject: Spirometry