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Cholinesterase inhibitor treatment in patients with delirium/Authors' reply
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Journal Article
Cholinesterase inhibitor treatment in patients with delirium/Authors' reply
2011
Overview
[...] we could not understand the delay in starting therapy for delirium (12 h on average). [...] mortality in the placebo group was very low (8%), which is surprising in a group of older patients (mean age 70 years) with a high risk of death (mean APACHE II score 19.6).\\n1 Further more, the suggestion that older people are more prone to delirium because of weaker immunity contrasts with evidence that it is reduced cholinergic tone that makes elderly people succeptible.2 We agree with Dimitri Gusmao and colleagues that ideally the delay between delirium onset and inclusion should have been shorter.
Publisher
Elsevier Limited
Subject
