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Multinational Observational Cohort Study of COVID-19-Associated Pulmonary Aspergillosis 1

by Nseir, Saad , Buil, Jochem B , Vanderbeke, Lore , Brüggemann, Roger J M , Ergün, Mehmet , Rijnders, Bart J A , Janssen, Nico A F , Dupont, Hervé , Tamion, Fabienne , Dunbar, Albert , van der Spoel, Hans I , Wauters, Joost , van Regenmortel, Niels , Reynders, Marijke , Maizel, Julien , Debavaye, Yves , Chouaki, Taieb , Lormans, Piet , Verweij, Paul E , Jacobs, Cato , Bourgeois, Marc , Lagrou, Katrien , Schouten, Jeroen A , Nyga, Rémy , van Dijk, Karin , van de Veerdonk, Frank L , Rutsaert, Lynn , Bouman, Catherine S C , Feys, Simon , Costa, Damien , Sendid, Boualem , Altenburg, Josje

in Cohort Studies / COVID-19 / Humans / Invasive Pulmonary Aspergillosis / Pulmonary Aspergillosis / SARS-CoV-2

2021

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Multinational Observational Cohort Study of COVID-19-Associated Pulmonary Aspergillosis 1

in Cohort Studies / COVID-19 / Humans / Invasive Pulmonary Aspergillosis / Pulmonary Aspergillosis / SARS-CoV-2

2021

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Multinational Observational Cohort Study of COVID-19-Associated Pulmonary Aspergillosis 1

in Cohort Studies / COVID-19 / Humans / Invasive Pulmonary Aspergillosis / Pulmonary Aspergillosis / SARS-CoV-2

2021

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Journal Article

Multinational Observational Cohort Study of COVID-19-Associated Pulmonary Aspergillosis 1

Nseir, Saad,

Buil, Jochem B,

Vanderbeke, Lore,

Brüggemann, Roger J M,

Ergün, Mehmet,

Rijnders, Bart J A,

Janssen, Nico A F,

Dupont, Hervé,

Tamion, Fabienne,

Dunbar, Albert,

van der Spoel, Hans I,

Wauters, Joost,

van Regenmortel, Niels,

Reynders, Marijke,

Maizel, Julien,

Debavaye, Yves,

Chouaki, Taieb,

Lormans, Piet,

Verweij, Paul E,

Jacobs, Cato,

Bourgeois, Marc,

Lagrou, Katrien,

Schouten, Jeroen A,

Nyga, Rémy,

van Dijk, Karin,

van de Veerdonk, Frank L,

Rutsaert, Lynn,

Bouman, Catherine S C,

Feys, Simon,

Costa, Damien,

Sendid, Boualem,

Altenburg, Josje

2021

Overview

We performed an observational study to investigate intensive care unit incidence, risk factors, and outcomes of coronavirus disease-associated pulmonary aspergillosis (CAPA). We found 10%-15% CAPA incidence among 823 patients in 2 cohorts. Several factors were independently associated with CAPA in 1 cohort and mortality rates were 43%-52%.

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Subject

Cohort Studies

/ COVID-19

/ Humans

/ Invasive Pulmonary Aspergillosis

/ Pulmonary Aspergillosis

/ SARS-CoV-2