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电针结合训练改善缺血性中风患者运动功能及血清脑损伤标志物的临床观察
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电针结合训练改善缺血性中风患者运动功能及血清脑损伤标志物的临床观察
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Journal Article
电针结合训练改善缺血性中风患者运动功能及血清脑损伤标志物的临床观察
2024
Overview
R246.6; 目的:观察电针结合常规语言和运动训练对缺血性中风患者肢体和语言功能、抑郁状况及血清脑损伤标志物的影响.方法:选取86例缺血性中风患者,采用随机抽签法分为观察组和对照组,每组43例.两组患者均接受脑卒中常规治疗,对照组加用常规语言和运动训练,观察组在对照组干预基础上加用电针治疗.比较两组患者治疗前后肢体功能评分、语言功能评分、抑郁状况评分、脑损伤标志物蛋白变化情况,评价两组治疗安全性.结果:治疗后两组患者Fugl-Meyer评分均较治疗前提高(P<0.05),观察组肢体功能Fugl-Meyer评分高于对照组(P<0.05).治疗后观察组语言功能评分高于对照组(P<0.05).治疗后观察组蒙哥马利抑郁评定量表(MADRS)各项评分均低于对照组(P<0.05).治疗后观察组脑损伤标志物心型脂肪酸结合蛋白(H-FABP)、胶质纤维酸性蛋白(GFAP)、膜联蛋白A7(ANXA7)水平均低于对照组(P<0.05).治疗期间两组患者不良反应发生率分别为14.0%和9.3%,组间差异无统计学意义(P>0.05).结论:电针联合语言及运动训练治疗缺血性中风疗效肯定,可促进患者肢体运动功能和语言功能恢复,抑制抑郁状况发生,降低脑损伤标志物水平,且安全性较好.
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