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هدفت الدراسة إلى التعرف على العلاقة بين تناقض إدراك الذات وآليات الدفاع لدى عينة من النساء غير المنجبات، والعلاقة الارتباطية بينهما. تكونت عينة الدراسة من (205) امرأة غير منجبة، تم اختيارهن بالطريقة المتيسرة. أظهرت نتائج الدراسة إلى وجود درجة مرتفعة من تناقض إدراك الذات لدى النساء غير المنجبات، وكما أشارت إلى وجود درجة متوسطة من استخدام آليات الدفاع وأخيرا توصلت الدراسة إلى وجود علاقة دالة إحصائيا بين تناقض إدراك الذات وآليات الدفاع لدى النساء غير المنجبات. حيث توصي الدراسة، بضرورة إخضاع النساء غير المنجابات لبرامج إرشادية للحد من تناقض إدراك الذات، وتقليل استخدام آليات الدفاع.

Acute coronary syndrome (ACS) is the leading cause of death worldwide despite advances in treatment and prevention measures. This study aimed to explore ACS treatment strategies (ischemia-guided vs early invasive) and risk factors among patients diagnosed with ACS in a tertiary care hospital in Palestine and to evaluate related outcomes regarding future events and standard clinical guidelines. This retrospective cohort study reviewed patient data from a Palestinian medical hospital. The study included 255 patients ≥ 18 years who were hospitalized between January 2021 and December 2021 and diagnosed with ACS. The data were analyzed using the Statistical Package for Social Science (SPSS). 71% of the participants were males. The mean age was 59.59±11.56 years. Smoking, diabetes, and hypertension were the most common risk factors. Unstable angina (UA) was the most prevalent ACS type, accounting for 43.1% (110) of cases, whereas NSTEMI accounted for 39.2% (100) and STEMI accounted for 17.6% (45) of cases. An ischemic-guided strategy approach was used in 71% (181) of the patients. Upon discharge, the most prescribed medication classes were antiplatelets (97.6%), statins (87.1%), PPIs (72.5%), and antihypertensives (71.8%). Treatment strategies were selected according to the clinical guidelines for most ACS types. ACS management in Palestine continues to evolve to overcome barriers, decrease patient mortality, and decrease hospital stay. UA and NSTEMI were the most common ACS diagnoses at admission, and the ischemic strategy was the most common modality. The findings of this study call for an increased awareness of CVD risk factors, resource availability, and adherence to clinical guidelines to improve patient outcomes and community health.

Antimicrobial resistance to ESKAPE pathogens ( spp). remains a major challenge in hospital settings. This study aimed to determine the ESKAPE antimicrobial resistance patterns and associated factors with multi-drug resistance strains among hospitalized patients in a single tertiary care medical hospital in Palestine. A single-center retrospective cross-sectional study was conducted by reviewing patients' electronic medical records and laboratory results from November 1, 2021, to November 30, 2022, at the Palestine Medical Complex in Palestine. The study included patients aged > 18 years who had been infected with ESKAPE pathogens 48 hours after hospital admission. This study included 231 patients, of whom 90.5% had MDR infections. In total, 331 clinical samples of ESKAPE pathogens were identified. was the most prevalent MDR pathogen (95.6%) with Carbapenem-resistant exceeding 95%, followed by (83.8%) with extended-spectrum cephalosporin resistance exceeding 90%, (68.2) with 85% oxacillin-resistance, (40%) with 20% vancomycin resistance, (22.6%) with 30% carbapenem resistance. Furthermore, emergent colistin resistance has been observed in , and . Risk factors for MDR infection included age (p< 0.035), department (p< 0.001), and invasive procedures such as IUC (p< 0.001), CVC (p< 0.000), and MV (p< 0.008). Patients diagnosed with MDR bacteria had increased 30-day mortality (p< 0.001). The findings of this study show alarming MDR among hospitalized patients infected with ESKAPE pathogens, with resistance to first-line antimicrobial agents and emerging resistance to colistin, minimizing treatment options. Healthcare providers and the Ministry of Health must take steps, adopt policies to prevent antimicrobial resistance, adhere to infection control guidelines, implement antimicrobial stewardship programs to prevent and limit the growing health crisis, and support research to discover new treatment options.

Hypertension (HTN) is a major risk factor of cardiovascular diseases (CVDs). Asprosin, a novel adipokine, has been linked to metabolic diseases; however, its role in HTN remains unclear. This study investigated the association between asprosin levels and HTN in 110 sex-matched participants. Sociodemographic, lifestyle, and family history data were collected, and anthropometric measurements and fasting blood samples were obtained to assess glucose, asprosin, and insulin levels. Insulin resistance and β-cell function were estimated using LogHOMA-IR and LogHOMA-β. Statistical analyses included t-tests, chi-square, Mann-Whitney U tests, receiver operating characteristic analysis with area under the curve (AUC), and ridge-penalized logistic regression. Cases reported higher stress levels and a greater maternal history of HTN compared with controls. Blood glucose, insulin, LogHOMA-IR and LogHOMA-β were all significantly elevated in cases. Median asprosin levels were higher in cases (98.7 ng/ml, IQR 57.7) than controls (65.4 ng/ml, IQR 55.4; p  < 0.001) and demonstrated good discriminatory ability for HTN (AUC = 0.827; cut-off point > 79.15 ng/ml), with notable sex differences, as males showed higher discriminatory ability compared with females. Elevated asprosin was associated with higher odds of HTN (β = 1.31, SE = 0.319; OR = 3.71, 95% CI: 1.99–6.93), though the association attenuated after adjusting for antihypertensive medication and other confounders. These findings suggest that asprosin may serve as a potential biomarker for HTN, warranting further investigation into its clinical relevance.

Background and Aims. COVID-19 emerged at the end of 2019 and was classified as a global pandemic in March 2020. Infected cases of SARS-CoV-2 experience symptoms during initial infection 2–14 days after virus exposure, and some symptoms and complications may persist after recovery. This study evaluated the onset/recovery time, postrecovery symptoms, complications, and factors affecting the health situation of recovered cases of COVID-19 in West Bank, Palestine. Methods. This cross-sectional study was conducted using a questionnaire based on related scientific articles and expert recommendations. It was distributed to recovered COVID-19 patients either face-to-face or online. Chi-square and Fisher’s exact tests were used to investigate the significant relationships. The data were analyzed using SPSS version 22. Findings. A total of 686 participants completed the questionnaire; the mean age was 28·1 ± 11·8. SARS-CoV-2 infection recovery time was 1–2 weeks in most participants. A total of 72·4% developed post-COVID-19 symptoms. Fatigue (260, 38.0%), loss of smell (224, 32.7%), headache (207, 30.7%), and joint pain (188, 27.4%) were the most reported postrecovery symptoms. In women, fatigue and headaches were the most common symptoms that persisted after recovery. Diabetic patients endured continuous muscle and joint pain. Interpretation. Patient health situation, recovery time, and symptoms post-COVID-19 infections are affected by many demographic factors and disease status.