Journal Article

Acute Coronary Syndrome: Treatment Strategies and Outcomes in Patients Admitted to a Tertiary Care Hospital in Palestine

Swaileh, Zain, Madia, Raed, Al-Shami, Ni'meh, Abumadi, Sarah, Hamad, Shahd, Abukhalil, Abdallah Damin, Ghanem, Aseel

2024

Overview

Acute coronary syndrome (ACS) is the leading cause of death worldwide despite advances in treatment and prevention measures. This study aimed to explore ACS treatment strategies (ischemia-guided vs early invasive) and risk factors among patients diagnosed with ACS in a tertiary care hospital in Palestine and to evaluate related outcomes regarding future events and standard clinical guidelines. This retrospective cohort study reviewed patient data from a Palestinian medical hospital. The study included 255 patients ≥ 18 years who were hospitalized between January 2021 and December 2021 and diagnosed with ACS. The data were analyzed using the Statistical Package for Social Science (SPSS). 71% of the participants were males. The mean age was 59.59±11.56 years. Smoking, diabetes, and hypertension were the most common risk factors. Unstable angina (UA) was the most prevalent ACS type, accounting for 43.1% (110) of cases, whereas NSTEMI accounted for 39.2% (100) and STEMI accounted for 17.6% (45) of cases. An ischemic-guided strategy approach was used in 71% (181) of the patients. Upon discharge, the most prescribed medication classes were antiplatelets (97.6%), statins (87.1%), PPIs (72.5%), and antihypertensives (71.8%). Treatment strategies were selected according to the clinical guidelines for most ACS types. ACS management in Palestine continues to evolve to overcome barriers, decrease patient mortality, and decrease hospital stay. UA and NSTEMI were the most common ACS diagnoses at admission, and the ischemic strategy was the most common modality. The findings of this study call for an increased awareness of CVD risk factors, resource availability, and adherence to clinical guidelines to improve patient outcomes and community health.

• Publisher: Dove Medical Press Limited,Taylor & Francis Ltd,Dove,Dove Medical Press
• Subject: Acute coronary syndrome / Acute coronary syndromes / Care and treatment / Clopidogrel / Cohort analysis / Comorbidity / Coronary heart disease / Coronary vessels / Data collection / Diabetes / early invasive strategy / Evidence-based medicine / Family medical history / Heart attacks / Hospital patients / Hospitals / Hypertension / Intubation / Ischemia / ischemia-guided strategy / Kidney diseases / Medical care / Medical records / Medical research / Medicine, Experimental / Mortality / non-st-elevation myocardial infarction / Obesity / Original Research / Palestinian Territories / Patient outcomes / Patients / Prevention / Quality management / Risk factors / st-elevation myocardial infarction / Statins / Statistics / Type 2 diabetes / unstable angina / Veins & arteries