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Background Pediatrics is one of the most important medical specialties in the Kingdom of Saudi Arabia) KSA) since it serves a large population. Therefore, the pediatrics residency program is considered one of the most important and competitive programs. Obtaining acceptance in Saudi programs depends mainly on the Saudi Commission for Health Specialties (SCFHS) score, then the applicant enrolls to do the interviews with the training centers in the accepted region. This study aimed to evaluate the factors used by pediatric program directors (PD) in accepting applicants in their pediatric residency program in KSA. Methods In this cross-sectional study, an online questionnaire consisting of 49 items was distributed among 76 current and former pediatric PDs in KSA. Participants were selected via non-probability convenience sampling. Data were collected and analyzed using the Social Sciences Statistical Package (SPSS version 26). Results Of the sample of PD studied, males represented 77.6%, while females represented 22.4%. Most of the PDs were over 50 years old. Most of them were former pediatric PDs (71.1%). The current study found that the Saudi Medical Licensing Exam was the most important factor [3.87 (0.89)] followed by services and electives [3.86 (0.65)], research [3.84 (0.83)], interview [3.77 (0.89)], GPA [3.50 (0.62)], and letter of recommendation [3.39 (0.76)]. Conclusions For those interested in pediatrics residency programs in KSA, this study recommends that seeking a high Saudi Medical Licensing Exam (SMLE) score, taking pediatric elective rotations during internship, and acquiring excellent basic knowledge in research were the most important aspects of pediatrics residency selection from the pediatrics PD’s perspective.

Background During the coronavirus 2019 (COVID-19) pandemic, Saudi Arabia implemented strict measures to prevent the entry and spread of the virus and to minimize its burden on society, including the use of online education as an alternative to traditional classroom learning. This study surveyed medical students from King Abdulaziz bin Saud University for Health Sciences-Riyadh to evaluate the factors affecting their satisfaction and experience with online learning. Methods This cross-sectional study was conducted from March to May 2021, using consecutive sampling and a population of approximately 700 medical students from King Saud bin Abdulaziz University of Health Sciences. This study was carried out through an online questionnaire. Results The survey received 277 responses with a response rate of 40%. About 15.3% of respondents believed that online learning productivity was poor, and 18.9% found it below average; however, 21.7% rated it as excellent. The level of anxiety while studying at home was rated as fine by 32.7%, while 21% felt very anxious, and the level of distraction was reported to be high, by 23.1%. Additionally, 64.4% of respondents preferred more online courses even after the COVID-19 crisis. Overall, 29.2% of respondents rated online learning as excellent, while 12.5% rated it as poor. We found a significant positive correlation between feeling isolated while studying at home and feeling anxious (r=0.618; p<0.001) and a significant positive correlation between productivity during online learning and the impact on grades (r=0.495; p<0.001). Conclusion This study found that online learning had benefits but also negatively impacted academic performance and mental health, highlighting the need for tailored support services. Further research is recommended, and medical students should have more theoretical online classes while keeping practical sessions on-site.

Fights, domestic violence and street crimes are the major causes of stab wounds in the Kingdom of Saudi Arabia (KSA). The objective of the study was to describe the nature and severity of stab wounds at a tertiary care hospital in KSA. A cross-sectional study, which included 106 patients, was conducted at the King Khalid Hospital and Prince Sultan Centre for Health Care in Al Kharj. The patients that fulfilled the inclusion criteria were recruited for the study after having confirmed their consent. The authors procured and analysed the patients' clinical notes to obtain information that was pertinent to the study. The authors recorded all data within a Microsoft Excel document. SPSS 22.0 was utilized for statistical analysis. Of 106 patients, the majority were adolescents and young adults under the age of 40 (n = 77). Eighty-seven point seven percent of patients were male and 84.0% were Saudis. Demographic details were tabulated. The top three causes were fights (20.8%) followed by domestic violence (18.9%) and street crime (17.0%). Degree of shock, stabbing zones, injury to vessels, nerves and bones, injury severity score (ISS) and Glasgow Coma Scale (GCS) were tabulated. The nature and severity of stab wounds should be carefully evaluated and properly managed, as these may lead to serious complications.

BackgroundSpinal muscular atrophy (SMA) is a severe genetic neuromuscular disorder characterized by muscle atrophy and weakness due to motor neuron loss. It results from mutations in the SMN1 gene, leading to insufficient SMN protein, which is essential for motor neuron survival. SMA manifests in varying degrees of severity, with subtypes classified based on the age of symptom onset and motor function impairment. SMA type 1 is the most severe, with early onset and significant respiratory and motor complications, while SMA types 2 and 3 have later onset and less severe symptoms. Recent advancements, such as the approval of Nusinersen, offer new hope in altering the disease’s progression and improving motor functions, respiratory outcomes, and survival rates across SMA types.ResultsThis systematic review included 10 studies. Significant improvements in motor function were observed, particularly in patients with SMA types 1, 2, and 3, as measured by scales, such as CHOP INTEND, HFMSE, and 6MWT. Respiratory function and survival outcomes were mixed, with some patients requiring ongoing ventilation support despite motor function improvements. The safety profile of Nusinersen was generally favorable, with mild to moderate adverse events such as headaches and back pain being the most common. Severe adverse events, though rare, included cases of aseptic meningitis and increased intracranial pressure, highlighting the need for careful monitoring during treatment.ConclusionsThis review confirms that Nusinersen is safe and effective for treating SMA across different types and severities. It improves motor and respiratory functions with manageable side effects. The findings support Nusinersen’s role in SMA treatment and provide valuable guidance for both clinical practice and future research. Early treatment initiation and attention to individual patient needs are emphasized to achieve the best outcomes.

Irritable bowel syndrome (IBS) is a commonly found global functional pathology with no detectable structural changes. It affects the quality of life and often coexists with psychiatric and somatic issues. We reviewed all articles published between 1990 and April 2023. The databases used for the data search were Google Scholar, Web of Science, Cochrane Library, and PubMed/MEDLINE. Ovid search engine was also used to broaden the search strategy. Predefined keywords, including \"Irritable bowel syndrome\" (MeSH) OR \"IBS\" (all fields), along with \"Saudi Arabia\" and \"Middle East,\" were used to avoid data loss and ambiguity. Any cross-sectional study that reported the prevalence of IBS in any gender, age, and group of the Saudi population was included. Data extraction was independently performed in duplicate to mitigate bias and data loss. Statistical analysis of proportion was conducted by using Miller (Freeman-Tukey double arcsine - exact inverse). Out of 350 records identified, only 38 studies were included in the quantitative synthesis. The total number of study participants was 26,567, on the basis of the predefined inclusion criteria of the study. StatsDirect software was used for the statistical analysis of the study parameters. Based on all 38 identified studies, the calculated pooled prevalence was 20.7% (95% confidence interval (CI) = 17.8% to 23.7% by applying random effects (DerSimonian-Laird method). IBS was identified in 21% (95% CI = 16.7% to 25.7%) of the general population, 22% (95% CI = 17.6% to 26.7%) of students, and 18.3% (95% CI = 13.3% to 23.9%) of healthcare workers. The pooled prevalence of IBS among the Saudi population was 20.7%. The pathophysiology of IBS is complexed and significantly affected by genetics, diet, cultural characteristics, age, anxiety, depression, stress, and sleep disorders. This study fills a gap in understanding IBS prevalence in Saudi Arabia, contributing valuable data to this region.

Pediatrics is one of the most important medical specialties in the Kingdom of Saudi Arabia) KSA) since it serves a large population. Therefore, the pediatrics residency program is considered one of the most important and competitive programs. Obtaining acceptance in Saudi programs depends mainly on the Saudi Commission for Health Specialties (SCFHS) score, then the applicant enrolls to do the interviews with the training centers in the accepted region. This study aimed to evaluate the factors used by pediatric program directors (PD) in accepting applicants in their pediatric residency program in KSA. In this cross-sectional study, an online questionnaire consisting of 49 items was distributed among 76 current and former pediatric PDs in KSA. Participants were selected via non-probability convenience sampling. Data were collected and analyzed using the Social Sciences Statistical Package (SPSS version 26). Of the sample of PD studied, males represented 77.6%, while females represented 22.4%. Most of the PDs were over 50 years old. Most of them were former pediatric PDs (71.1%). The current study found that the Saudi Medical Licensing Exam was the most important factor [3.87 (0.89)] followed by services and electives [3.86 (0.65)], research [3.84 (0.83)], interview [3.77 (0.89)], GPA [3.50 (0.62)], and letter of recommendation [3.39 (0.76)]. For those interested in pediatrics residency programs in KSA, this study recommends that seeking a high Saudi Medical Licensing Exam (SMLE) score, taking pediatric elective rotations during internship, and acquiring excellent basic knowledge in research were the most important aspects of pediatrics residency selection from the pediatrics PD's perspective.

Background Papillary thyroid cancer (PTC), a well-differentiated form of cancer, accounts for the majority of thyroid malignancies, and the incidence of PTC is on the rise. While the rate of PTC recurrence is considered to be low, there are broad spectrums of clinical and biological behavior that can lead to disease recurrence. The American Thyroid Association (ATA) risk stratification system for differentiated thyroid cancer is used as a prognostic tool to guide decision-making and management strategies most likely to achieve a favorable outcome. Aim This study aimed to estimate the prevalence of PTC recurrence in each category of the ATA risk stratification system and determine the appropriate iodine dose to be administered at the King Abdulaziz Medical City Endocrinology Clinic in Riyadh, Saudi Arabia. Methods A cross-sectional retrospective chart review was conducted on adult patients with PTC who underwent thyroidectomy procedures at the King Abdullah Specialized Children's Hospital (KASCH) Endocrinology Clinic in Riyadh between 2015 and 2023. IBM SPSS (Statistical Package for the Social Sciences) version 25 (IBM Corp., Armonk, NY) was used for data analysis. Results Of the 697 patients included in the study, 82.4% were females. About 5% had suffered from PTC recurrence, and 54.4% had low-risk stratification. In addition, more than half (52.1%) had received radioactive iodine (RAI). The recurrence of PTC was significantly associated with age (P = 0.019), ATA risk stratification (P = 0.0001), RAI therapy (P = 0.001), and iodine dosage (P = 0.013). Conclusion Both low PTC recurrence rates and low-risk stratification were observed among the PTC patients. The risk factors relating to PTC recurrence included high-risk stratification, advanced age, RAI therapy, and the dosage of RAI administered.

This study aimed to assess the level of readiness among primary school teachers to handle sports injuries in Saudi Arabia.  A structured questionnaire was applied to collect information on teachers, training, knowledge, attitudes, and perceived barriers in managing common sports injuries. Descriptive analysis was performed for demographics and baseline information. Pearson's Chi-squared test and Fisher's exact test were used to assess the determinants of first-aid attitude. Multiple logistic regression was also used to evaluate the determinants of first-aid knowledge. A total number of 535 teachers participated in this study. Most teachers (64.3%) reported an occurrence of sports injury once per month. Only 373 (67.72%) perceived the first aid kit to be readily accessible. The majority (95.89%) of teachers reported familiarity with conducting first aid and 87.38% expressed interest and willingness to learn. Social media was the primary resource of first aid knowledge (57.94%). Logistic regression showed that male sex (OR: 0.51, 95% CI: 0.26, 0.95; p-value = 0.036) and experiencing sports injuries once per month (OR: 0.39, 95% CI: 0.16, 0.84; p-value = 0.024) were associated with negative attitude toward first aid. However, having 10-20 years of experience (OR: 2.46, 95% CI: 1.09, 5.62; p-value = 0.031) or more than 20 years of experience was associated with more positive attitude toward first aid (OR: 6.47, 95% CI: 2.18, 19.8; p-value ≤ 0.001). Furthermore, accessing first aid information from digital media and healthcare professionals compared to books was significantly associated with increased knowledge about first aid. Easy accessibility to first aid was also significantly associated with increased knowledge about first aid. While many teachers feel prepared, the primary source of their first aid knowledge is unattributed social media content rather than certified training. Certified first aid training programs are needed to help in ensuring the quality emergency management of sports injuries.

Neuromyelitis optica spectrum disorders (NMOSDs) are central nervous system inflammatory conditions, now recognized to involve the brain, often identified by aquaporin-4 (AQP4) antibodies. We aimed to summarize the characteristics of adult NMOSD patients compared to multiple sclerosis (MS). A computerized search was conducted on MEDLINE via PubMed, Web of Science, and ProQuest using the relevant keywords. Three independent reviewers performed two-stage screening and data extraction. The Review Manager 5.4 program (Cochrane Collaboration, Windows, London, UK) was used for the analysis. The Joanna Briggs Institute (JIB) tool was used for the quality of included studies. Twenty-three articles were included. NMOSD patients were associated with older age at presentation and higher Expanded Disability Status Scale (MD = 3.88, 95% CI: 1.80 to 5.97, P = 0.0003) and (MD = 1.15, 95% CI: 0.58 to 1.72, P < 0.0001), respectively. The risk of NMOSD in females was significantly higher than MS (OR = 2.21, 95% CI: 1.41 to 3.46, P = 0.0005). Patients with NMOSD were associated with a lower risk of extrapyramidal symptoms (OR = 0.26, 95% CI: 0.11 to 0.60, P < 0.01), brainstem involvement symptoms (OR = 0.32, 95% CI: 0.16 to 0.64, P < 0.01), and developing brain lesions compared to MS (OR = 0.08, 95% CI: 0.03 to 0.18, P < 0.00001). The current evidence suggests that both NMOSD and MS have different demographic, clinical, and lesion characteristics. There is a need for additional validation of the identified differences compared with MS due to the lack of long-term systematic imaging investigations in NMOSD.Neuromyelitis optica spectrum disorders (NMOSDs) are central nervous system inflammatory conditions, now recognized to involve the brain, often identified by aquaporin-4 (AQP4) antibodies. We aimed to summarize the characteristics of adult NMOSD patients compared to multiple sclerosis (MS). A computerized search was conducted on MEDLINE via PubMed, Web of Science, and ProQuest using the relevant keywords. Three independent reviewers performed two-stage screening and data extraction. The Review Manager 5.4 program (Cochrane Collaboration, Windows, London, UK) was used for the analysis. The Joanna Briggs Institute (JIB) tool was used for the quality of included studies. Twenty-three articles were included. NMOSD patients were associated with older age at presentation and higher Expanded Disability Status Scale (MD = 3.88, 95% CI: 1.80 to 5.97, P = 0.0003) and (MD = 1.15, 95% CI: 0.58 to 1.72, P < 0.0001), respectively. The risk of NMOSD in females was significantly higher than MS (OR = 2.21, 95% CI: 1.41 to 3.46, P = 0.0005). Patients with NMOSD were associated with a lower risk of extrapyramidal symptoms (OR = 0.26, 95% CI: 0.11 to 0.60, P < 0.01), brainstem involvement symptoms (OR = 0.32, 95% CI: 0.16 to 0.64, P < 0.01), and developing brain lesions compared to MS (OR = 0.08, 95% CI: 0.03 to 0.18, P < 0.00001). The current evidence suggests that both NMOSD and MS have different demographic, clinical, and lesion characteristics. There is a need for additional validation of the identified differences compared with MS due to the lack of long-term systematic imaging investigations in NMOSD.

Newer trends in shade matching have been driven by the market need for superior grade esthetic restorations. Modernized shade guides, obtainability of shade-taking devices, and research in the field of human color vision have ameliorated the capability of dentists to attain outstanding color-matched restorations. A detailed knowledge of natural teeth' appearance features is needed along with these new devices to increase shade-matching results.