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This is a multi-wavelength study to examine the G45.804-0.355 massive star-forming region (SFR) and its environs. Using MeerKAT with angular resolution (θ) of 8″ at 1.28 GHz, we identify for the first time, a faint radio continuum emission core in G45.804-0.355. At 1.3 mm, ALMA observations (θ∼0″ 7) resolved the core into multiple dust continuum condensations including MM1 which was found to be the primary massive dust dense core in the region (mass M c∼ 54.3 M ⊙). The dust continuum shows an arm-like extended emission within which other dense cores are situated. The velocity gradient of the MM1 core indicates that the source is associated with a rotation gas motion. The red- and blue-shifted lobes overlap at the position of MM1. The compact morphology of the 4.5 μm IR emission, the presence of spiral arms and overlapping of the red- and blue-shifted lobes suggest a face-on geometry of G45.80-40.355.

V4334 Sgr (a.k.a. Sakurai's object) is the central star of an old planetary nebula that underwent a very late thermal pulse a few years before its discovery in 1996. We have been monitoring the evolution of the optical emission line spectrum since 2001. The goal is to improve the evolutionary models by constraining them with the temporal evolution of the central star temperature. In addition the high resolution spectral observations obtained by X-shooter and ALMA show the temporal evolution of the different morphological components.

The methanol multi-beam (MMB) survey has produced the largest and most complete catalogue of Galactic 6.7-GHz methanol masers to date. 6.7-GHz methanol masers are exclusively associated with high-mass star formation, and as such provide invaluable insight into the Galactic distribution and properties of high-mass star formation regions. I present the statistical properties of the MMB catalogue and, through the calculation of kinematic distances, investigate the resolution of distance ambiguities and explore the Galactic distribution.

The results of the first complete survey for 6668-MHz CH3OH and 6035-MHz excited-state OH masers in the Small and Large Magellanic Clouds are presented. A new 6668-MHz CH3OH maser in the Large Magellanic Cloud has been detected towards the star-forming region N 160a, together with a new 6035-MHz excited-state OH maser detected towards N 157a. We also re-observed the previously known 6668-MHz CH3OH masers and the single known 6035-MHz OH maser. Neither maser transition was detected above ~0.13 Jy in the Small Magellanic Cloud. All observations were initially made using the CH3OH Multibeam (MMB) survey receiver on the 64-m Parkes radio telescope as part of the overall MMB project. Accurate positions were measured with the Australia Telescope Compact Array (ATCA). In a comparison of the star formation maser populations in the Magellanic Clouds and our Galaxy, the LMC maser populations are demonstrated to be smaller than their Milky Way counterparts. CH3OH masers are under-abundant by a factor of ~50, whilst OH and H2O masers are a factor of ~10 less abundant than our Galaxy.

This study presents a detailed analysis of the GAL045.804-0.356 massive star-forming clump. A high-angular resolution and sensitivity observations were conducted using MeerKAT at 1.28 GHz and ALMA interferometer at 1.3 mm. Two distinct centimetre radio continuum emissions (source A and source B) were identified within the clump. A comprehensive investigation was carried out on source A, the G45.804-0.355 star-forming region (SFR) due to its association with Extended Green Object (EGO), 6.7 GHz methanol maser and the spatial coincidence with the peak of the dust continuum emission at 870 \\(\\)m. The ALMA observations revealed seven dense dust condensations (MM1 to MM7) in source A. The brightest (\\(S_ \\) 87 mJy) and massive main dense core, MM1, was co-located with the 6.7 GHz methanol maser. Explorations into the kinematics revealed gas motions characterised by a velocity gradient across the MM1 core. Furthermore, molecular line emission showed the presence of an extended arm-like structure, with a physical size of 0.25 pc \\(\\) 0.18 pc (\\(\\) 50000 au \\(\\) 30000 au) at a distance of 7.3 kpc. Amongst these arms, two arms were prominently identified in both the dust continuum and some of the molecular lines. A blue-shifted absorption P-Cygni profile was seen in the H\\(_2\\)CO line spectrum. The findings of this study are both intriguing and new, utilising data from MeerKAT and ALMA to investigate the characteristics of the AGAL45 clump. The evidence of spiral arms, the compact nature of the EGO and \\(<\\) 2 km s\\(^-1\\) velocity gradient are all indicative of G45.804-0.355 being oriented face-on.

We report a patient with rapidly accelerating HIV dementia accompanied by seizures and an unusual movement disorder despite highly potent antiretroviral therapy. This clinical constellation was associated with the non-parenteral use of methamphetamine and cocaine. Fractional enhancement time on post contrast magnetic resonance imaging studies revealed a progressive breakdown of the blood brain barrier particularly in the basal ganglia. The movement disorder but not the dementia responded to a combination of dopamine replacement and anticholinergic therapy. While the movement disorder may have been unmasked by concomitant anticonvulsant therapy, we suggest in this instance, that prior drug abuse synergized with HIV to cause a domino effect on cerebral function. Careful attention and analysis to histories of remote non-injecting drug abuse may help substantiate our hypothesis.

Context. The fragmentation of massive molecular clumps into smaller, potentially star-forming cores plays a key role in the processes of high-mass star formation. The ALMAGAL project offers high-resolution data to investigate these processes across various evolutionary stages in the Galactic plane. Aims. This study aims at correlating the fragmentation properties of massive clumps, obtained from ALMA observations, with their global physical parameters (e.g., mass, surface density, and temperature) and evolutionary indicators (such as luminosity-to-mass ratio and bolometric temperature) obtained from Herschel observations. It seeks to assess whether the cores evolve in number and mass in tandem with their host clumps, and to determine the possible factors influencing the formation of massive cores (M > 24M_\\odot). Methods. We analyzed the masses of 6348 fragments, estimated from 1.4 mm continuum data for 1007 ALMAGAL clumps. Leveraging this unprecedentedly large data set, we evaluated statistical relationships between clump parameters, estimated over about 0.1 pc scales, and fragment properties, corresponding to scales of a few 1000 au, while accounting for potential biases related to distance and observational resolution. Our results were further compared with predictions from numerical simulations. Results. The fragmentation level correlates preferentially with clump surface density, supporting a scenario of density-driven fragmentation, whereas it does not show any clear dependence on total clump mass. Both the mass of the most massive core and the core formation efficiency show a broad range and increase on average by an order of magnitude in the intervals spanned by evolutionary indicators such as clump dust temperature and the luminosity-to-mass ratio. This suggests that core growth continues throughout the clump evolution, favoring clump-fed over core-fed theoretical scenarios.

We present deep ALMA dust continuum observations for a sample of luminous (\\(M_{\\rm UV} < -22\\)) star-forming galaxies at \\(z \\simeq 7\\). We detect five of the six sources in the far-infrared (FIR), providing key constraints on the obscured star-formation rate (SFR) and the infrared-excess-\\(\\beta\\) (IRX-\\(\\beta\\)) relation without the need for stacking. Despite the galaxies showing blue rest-frame UV slopes (\\(\\beta \\simeq -2\\)) we find that 35-75 percent of the total SFR is obscured. We find the IRX-\\(\\beta\\) relation derived for these \\(z \\simeq 7\\) sources is consistent with that found for local star-burst galaxies. Using our relatively high-resolution (FWHM \\(\\simeq 0.7\\,{\\rm arcsec}\\)) observations we identify a diversity of dust morphologies in the sample. We find both compact emission that appears offset relative to the unobscured components and extended dust emission that is co-spatial with the rest-frame UV light. In the majority of the sources we detect strong rest-frame UV colour gradients (with up to \\(\\Delta \\beta \\simeq 0.7\\)-\\(1.4\\)) as probed by the multi-band UltraVISTA ground-based data. The observed redder colours are spatially correlated with the location of the FIR detection. Our results show that even in bright Lyman-break galaxies at \\(z \\simeq 7\\) the peak of the star-formation is typically hosted by the fainter, redder, regions in the rest-frame UV, which have an obscured fraction of \\(f_{\\rm obs} \\ge 0.8\\). As well as demonstrating the importance of dust obscured star-formation within the Epoch of Reionization, these observations provide an exciting taster of the rich spatially resolved datasets that will be obtained from JWST and high-resolution ALMA follow-up at these redshifts.

The study of molecular line emission is crucial to unveil the kinematics and the physical conditions of gas in star-forming regions. Our aim is to quantify the reliability of using individual molecular transitions to derive physical properties of the bulk of the H2 gas, looking at morphological correlations in their overall integrated molecular line emission with the cold dust. For this study we selected transitions of H2CO, CH\\(_3\\)OH, DCN, HC\\(_3\\)N, CH\\(_3\\)CN, CH\\(_3\\)OCHO, SO, and SiO and compared them with the 1.38 mm dust continuum emission at different spatial scales in the ALMAGAL sample, that observed a total of 1013 targets covering all evolutionary stages of the high-mass star-formation process and different conditions of clump fragmentation. We used the method of the histogram of oriented gradients (HOG) implemented in the tool astroHOG to compare the morphology of integrated line emission with maps of the 1.38 mm dust continuum emission. Moreover, we calculated the Spearman's correlation coefficient, and compared it with our astroHOG results. Only H\\(_2\\)CO, CH\\(_3\\)OH, and SO show emission on spatial scales comparable with the diffuse continuum emission. However, from the HOG method, the median correlation of the emission of each of these species with the continuum is only \\(\\)24-29%. In comparison with the dense fragments these molecular species still have low values of correlation. On the other hand DCN, HC\\(_3\\)N, CH\\(_3\\)CN, and CH\\(_3\\)OCHO show a good correlation with the dense dust fragments, above 60%. The worst correlation is seen with SiO, both with the extended continuum emission and with compact sources. From the comparison of the results of the HOG method and the Spearman's correlation coefficient, the HOG method gives much more reliable results than the intensity-based coefficient in estimating the level of similarity of the emission morphology.

We use data from the ALMA Evolutionary Study of High Mass Protocluster Formation in the Galaxy (ALMAGAL) survey to study 100 ALMAGAL regions at \\(\\sim\\) 1 arsecond resolution located between \\(\\sim\\) 2 and 6 kpc distance. Using ALMAGAL \\(\\sim\\) 1.3mm line and continuum data we estimate flow rates onto individual cores. We focus specifically on flow rates along filamentary structures associated with these cores. Our primary analysis is centered around position velocity cuts in H\\(_2\\)CO (3\\(_{0,3}\\) - 2\\(_{0,2}\\)) which allow us to measure the velocity fields, surrounding these cores. Combining this work with column density estimates we derive the flow rates along the extended filamentary structures associated with cores in these regions. We select a sample of 100 ALMAGAL regions covering four evolutionary stages from quiescent to protostellar, Young Stellar Objects (YSOs), and HII regions (25 each). Using dendrogram and line analysis, we identify a final sample of 182 cores in 87 regions. In this paper, we present 728 flow rates for our sample (4 per core), analysed in the context of evolutionary stage, distance from the core, and core mass. On average, for the whole sample, we derive flow rates on the order of \\(\\sim\\)10\\(^{-4}\\) M\\(_{sun}\\)yr\\(^{-1}\\) with estimated uncertainties of \\(\\pm\\)50%. We see increasing differences in the values among evolutionary stages, most notably between the less evolved (quiescent/protostellar) and more evolved (YSO/HII region) sources. We also see an increasing trend as we move further away from the centre of these cores. We also find a clear relationship between the flow rates and core masses \\(\\sim\\)M\\(^{2/3}\\) which is in line with the result expected from the tidal-lobe accretion mechanism. Overall, we see increasing trends in the relationships between the flow rate and the three investigated parameters; evolutionary stage, distance from the core, and core mass.