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"Englehart, Michael S"
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Splenectomy leads to a persistent hypercoagulable state after trauma
2010
It was hypothesized that splenectomy following trauma results in hypercoagulability.
A prospective, nonrandomized, single-center study was performed to evaluate coagulation parameters in trauma patients with splenic injury.
Patients with splenectomy (n = 30) and nonoperative management (n = 50) were enrolled. Splenectomy patients were older, had higher Injury Severity Scores, and had longer intensive care unit and hospital stays (
P < .05). Splenectomy patients had significantly increased white blood cell counts and platelet counts at baseline and follow-up (
P < .01). Fibrinogen was initially elevated in both groups and remained elevated in the splenectomy group (
P < .05). Tissue plasminogen activator, plasminogen activator inhibitor–1, and activated partial thromboplastin time were higher in splenectomy patients only at baseline (
P < .05). Baseline thromboelastography showed faster fibrin cross-linking and enhanced fibrinolysis following splenectomy (
P < .05). Only clot strength was greater at follow-up in the splenectomy group (
P < .01). Deep venous thrombosis developed in 7% of splenectomy patients and no control patients (
P = .03).
A significant difference in deep venous thrombosis formation was noted, and coagulation assays indicated persistent hypercoagulability following splenectomy for trauma.
Journal Article
The Montana Interfacility Blood Network: A Novel Lifesaving “Hand-off” for the Optimal Care of Rural Patients
by
Riha, Gordon
,
Englehart, Michael
,
Arnold, Sadie
in
Biological products
,
Blood products
,
Blood transfusion
2024
The state of Montana encompasses and defines rural health care as it is known in the United States (US) today. This vast area is punctuated by pockets of health care availability with varying access to blood products for transfusion. Furthermore, timely transport is frequently challenged by weather that may limit air transportation options, resulting in multiple hours in ground transport to definitive care.
The Montana State Trauma Care Committee (MT-STCC) developed the Montana Interfacility Blood Network (MT-IBN) to ensure blood availability in geographically distanced cases where patients may otherwise not survive. The index case that led to the formal development of the MT-IBN is described, followed by a second case illustrating the IBN process.
This process and development manuscript details the innovative efforts of MT-STCC to develop this fledgling idea unique to rural US health care. We review guidelines that have been developed to define broad aspects of the MT-IBN including the reason to share resources, proper packaging, paperwork necessary for transfer, and how to provide resources directly to the patient. Finally, we describe implementation within the state.
The MT-IBN was developed by MT-STCC to facilitate the hand-off of lifesaving blood to patients being transported by ground to definitive care in Montana without having to stop at an intermediary facility. This has already led to lives saved in areas that are limited in blood availability due to rurality.
Journal Article
Beyond capacity: an EAST multicenter mixed-methods study exploring surgeon perceptions on patient ratios in acute care surgery
by
Knowlton, Lisa Marie
,
Holleman, Gerrit
,
Shayn Martin, R
in
Burnout
,
Critical care
,
Delivery of Health Care
2025
BackgroundOptimal provider-to-patient (PtP) ratios in acute care surgery (ACS) remain undefined despite their importance for care quality and provider sustainability. This study aimed to understand surgeon perspectives on maximum ideal ratios across trauma, emergency general surgery (EGS) and surgical intensive care unit (SICU) services.MethodsThis multicenter mixed-methods study combined quantitative surveys and semistructured interviews with ACS surgeons at level I/II trauma centers across the USA (1 August 2023–19 April 2024). Service line census data were also collected. Interviews were recorded, transcribed and qualitative analysis performed; surveys were analyzed with descriptive statistics.ResultsFifty-two interviews were completed. Survey response rate was 50.3% (212/421 eligible division leadership and faculty) from 40 centers across 24 states. The perceived maximum safe patient load for trauma and EGS was <20 patients when working independently, and up to 40 patients with full team support. SICU ratios were lower with most reporting ≤10 patients for independent coverage and ≤20 with team support. Regarding appropriate patient loads for junior residents and advanced practice providers, most respondents recommended ≤10 patients for trauma/EGS and ≤7 for SICU. For senior residents, most recommended ≤13 patients for trauma/EGS and ≤7 for SICU. Notably, 72% of centers exceeded their own leadership-recommended maximums for at least one service line. Qualitative analysis revealed patient acuity, team experience and competing demands as key workload modulators, with concerns about care quality degradation and burnout at higher ratios.ConclusionsThis study establishes potential upper threshold benchmarks for ACS PtP ratios with strong agreement across institutions. Division leadership should consider developing staffing models that account for patient acuity and service complexity while implementing escalation protocols for sustained high workloads. Current practices frequently exceed maximum ideal ratios, highlighting the need for evidence-based staffing guidelines that balance financial constraints with mounting evidence linking workload intensity and density to adverse outcomes.Level of evidenceIV.
Journal Article
Use of Leukoreduced Blood Does Not Reduce Infection, Organ Failure, or Mortality Following Trauma
by
Riha, Gordon
,
Gee, Arvin C.
,
Wiesberg, Tracy T.
in
Abdominal Surgery
,
Acute Respiratory Distress Syndrome
,
Analysis of Variance
2009
Background
Leukoreduced (LR) blood has been demonstrated to reduce morbidity and mortality in high-risk surgical patients, but not in trauma patients. The objective of the present study was to determine the effect of LR blood on morbidity and mortality. We hypothesized that the use of LR blood does not improve outcome in trauma patients.
Methods
This study was a retrospective cohort analysis of trauma patients transfused at a level 1 Trauma Center from 2001 to 2004. Between 2002 and 2003, LR blood was transfused. Prior to that time and subsequent to it, non-leukoreduced (NLR) blood was transfused. This created two historical comparison groups. Data collected included patient demographics, units of blood transfused, intensive care unit (ICU) and hospital days, ventilator days, injury severity score (ISS), mortality, presence of acute respiratory distress syndrome (ARDS), and infectious complications. A multiple organ dysfunction syndrome (MODS) score was calculated.
Results
The distribution of patients was as follows: 284 patients received only NLR blood, 153 received only LR blood, and 58 received at least one unit of each. The mean ISS was similar (NLR: 26, LR: 24;
P
> 0.1). No differences were seen between groups in units transfused (6.2 vs. 5.5), number of ICU days (8.2 vs. 9.0), number of hospital days (16.9 vs. 18.6), number of ventilator days (6.1 vs. 5.7), incidence of ARDS (8.3% vs. 8.5%), MODS score (5.5 vs. 5.9), mortality rate (15.1% vs. 15.7%), or infection rate (36% vs. 30%) (
P
> 0.1).
Conclusions
This study represents the largest series comparing trauma patients who received either LR or standard blood transfusions. The use of LR blood does not improve outcome in trauma patients.
Journal Article
Home Enteral Nutrition Complications: A Nutrition Support Clinic Experience
2017
Trade Publication Article
Proceedings of the first workshop on Peripheral Machine Interfaces: going beyond traditional surface electromyography
by
Ajoudani, Arash
,
Marković, Marko
,
Scheme, Erik
in
Aerospace engineering
,
Amputation
,
Artificial intelligence
2014
One of the hottest topics in rehabilitation robotics is that of proper control of prosthetic devices. Despite decades of research, the state of the art is dramatically behind the expectations. To shed light on this issue, in June, 2013 the first international workshop on Present and future of non-invasive peripheral nervous system (PNS)-Machine Interfaces (MI; PMI) was convened, hosted by the International Conference on Rehabilitation Robotics. The keyword PMI has been selected to denote human-machine interfaces targeted at the limb-deficient, mainly upper-limb amputees, dealing with signals gathered from the PNS in a non-invasive way, that is, from the surface of the residuum. The workshop was intended to provide an overview of the state of the art and future perspectives of such interfaces; this paper represents is a collection of opinions expressed by each and every researcher/group involved in it.
Journal Article
The Centrality of Context in Learning from Further Class Size Research
2007
Educational researchers have conducted numerous studies regarding the effects of class size on student learning, yet the disparity of their findings make it difficult to draw overall conclusions. This paper first provides a description of some of the major class size studies in an effort to illustrate this point. Next, a research approach is suggested which might yield more definitive conclusions by carefully accounting for the additional contextual factors which surround class size. In addition to giving particular attention to context, this involves focusing on the mediating effects between class size and achievement and measuring achievement with classroom-level assessments.
Journal Article
Enteral Nutrition Support Following Gastroparesis and Chronic Radiation Enteritis
2016
Trade Publication Article
UFE program: a service line opportunity for U.S. hospitals
by
Amir, Leah D
,
Englehart, Michael
,
Lukhard, Kenneth W
in
Care and treatment
,
Company business management
,
Diagnosis
2009
Uterine fibroid embolization (UFE) is a nonsurgical procedure performed by an interventional radiologist to treat uterine fibroids, the most common solid pelvic, benign tumors occurring in women and one of the most prevalent indications for hysterectomies. Most hospitals already have the resources in place to establish an effective UFE program in collaboration with interventional radiologists. Such collaborations, exploiting existing resources, hold the key to many attractive service-line opportunities that exist for hospitals in today's financially stressed healthcare marketplace.
Journal Article