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The following case study clarifies how these three different functions of mission are discursively entangled with one another. Mission as a bridge-builder (between people, cultures, and religions of different origin), as a traitor (cooperating with corrupt colonial and imperial powers), and as a victim (finding misery and death on the mission field). Each of these three terms (bridge-builder, traitor, victim) is, to an extent, applicable to the events that took place during the night of 19–20 October 1896 in Akeri on the slopes of Mount Meru (former German East Africa, today Tanzania). Using the concept of entanglement history, I will analyze the death of two young German missionaries of the Lutheran Leipzig Mission, “caught in the crossfire” between the African community to be outreached and the German colonial military. We will see how various symbolic systems collide in the year 1896 at Akeri. The systems are represented by: (1) German Lutheran missions activities; (2) A German colonial and military expedition; and (3) The resistance of African Maasai societies’ leadership. “Akeri 1896” (I will continue to refer to this event specifically as “Akeri 1896” throughout the article) had become in the following 100 years a complex entanglement of metaphoric meanings. The same event can be a placeholder for victory, for defeat, for disaster, for martyrdom, for Christ-centredness (of the missionaries in their own perception), as well as for evil-centredness (the Africans in their perception of the Western foreigners).

Medicinal mushrooms are widely used in East Asia for the treatment of various diseases, especially in complementary cancer care. While there is a growing interest in medicinal mushrooms in Western countries and an increasing number of pre-clinical studies indicate distinct anti-cancer and regenerative properties, little is known about their potential relevance for clinical practice. This review aims to provide an overview of the clinical evidence, significance and potential role of medicinal mushrooms in complementary cancer care. Scientific databases for (randomized) controlled clinical trials evaluating whole spectrum formulations of medicinal mushrooms (mushroom powder and mushroom extracts) in cancer patients during and/or after conventional oncological treatment were searched. Eight studies met our inclusion criteria (eight randomized controlled trials, one controlled clinical trial). The medicinal mushrooms investigated were Agaricus sylvaticus (two trials), Agaricus blazei murill (two trials), Antrodia cinnamomea (one trial), Coriolus versicolor (one trial) and Ganoderma lucidum (three trials); all were compared to placebo and administered orally. A variety of cancer entities, outcomes and treatment durations were observed. Study results suggested beneficial effects of medicinal mushrooms, particularly quality of life and reduction of adverse effects of conventional therapies. Also, positive effects on antitumor activity and immunomodulation were reported, e.g., an increased activity of natural killer cells. In addition, results might suggest a longer survival of cancer patients receiving mushroom preparations, although in most studies this was not significant when compared to placebo. Adverse events of treatment with medicinal mushrooms were poorly reported; gastrointestinal reactions and a decrease in platelet cell count occurred in some cases. The methodological quality of most studies was generally unsatisfying and most results were insufficiently reported in several respects. Medicinal mushrooms may have a therapeutic potential for cancer patients during and after conventional oncological care with regards to quality of life, reduction of adverse effects of conventional care and possibly other surrogate parameters like immune function. There is an urgent need to investigate the safety and possible interactions of medicinal mushrooms. High-quality clinical research is warranted in order to clarify the potential of medicinal mushrooms in cancer therapy.

Operationalizing whistleblowing in a valid paradigm is an important yet challenging endeavor. In the present article, we review four categories of whistleblowing paradigms—scenario studies, autobiographical recalls, immersive behavioral paradigms, and economic games—and discuss how they capture the definitory features of whistleblowing. Moreover, we evaluate the strengths and weaknesses of each paradigm along selected psychometric criteria. Our review suggests that each of these paradigms comes with individual strength and weaknesses regarding the robustness against socially desirable responding, their efficiency, and whether or not they avoid using deception. We call for future research to conduct multi-method studies combining the four categories of whistleblowing paradigms within the same sample in order to test their convergence empirically.

Self-interacting dark matter (SIDM) is promising to solve or at least mitigate small-scale problems of cold collisionless dark matter. N-body simulations have proven to be a powerful tool to study SIDM within the astrophysical context. However, it turned out to be difficult to simulate dark matter (DM) models that typically scatter about a small angle, for example, light mediator models. We developed a novel numerical scheme for this regime of frequent self-interactions that allows for N-body simulations of systems like galaxy cluster mergers or even cosmological simulations. We have studied equal and unequal mass mergers of galaxies and galaxy clusters and found significant differences between the phenomenology of frequent self-interactions and the commonly studied large-angle scattering (rare self-interactions). For example, frequent self-interactions tend to produce larger offsets between galaxies and DM than rare self-interactions.

Hexagonal boron nitride (hBN), a two-dimensional (2D) material, garners interest for hosting bright quantum emitters at room temperature. While crystallographic defects are widely believed to be the source of these emitters, their exact nature, especially for visible frequencies, remains debated. Carbon impurities are frequently implicated, though their precise role is unclear, and extrinsic organic molecules at the hBN-substrate interface have also been proposed as contributors. In this study, we systematically explore the formation of luminescent emitters through irradiation engineering. Our results confirm that low-energy oxygen irradiation followed by annealing is key to forming visible quantum emitters in hBN. Notably, post-annealing in carbon-rich atmospheres significantly increases emitter density, reinforcing carbon’s potential role. We also find that hBN crystallographic quality influences emitter generation, with low-quality hBN producing nearly 20 percent more emitters than high-quality samples. While the formation of extrinsic organic molecules during high-temperature annealing cannot be ruled out, crystallographic defects formed during irradiation are central to emitter creation. We infer that these defects may promote the formation of few-atom luminescent centers and serve as molecular pinning sites. Our systematic study and findings advance the understanding of the formation of visible frequency quantum emitters in hBN.

Ultra high frequency radio frequency identification (UHF RFID) is becoming a key technology in the Internet of Things. It allows the implementation of batteryless and wireless nodes, including sensors and actuators. Due to its possible transmission range of >10 m and potential to carry critical information, security is a highly important topic. For this reason, the International Organization for Standardization has published several crypto suites for UHF RFID within the ISO-29167 standard in 2014. Recently, research has focused on implementing those encryption features on the transponder side. However, currently no crypto enabled UHF RFID readers are available. In order to cope with the rapid development in this field, ‘open’ and flexible readers based on software defined radios are needed. They make it possible to quickly adapt the protocol and to test new functionalities such as encryption. This paper deals with the first implementation of the ISO 29167-19 standardized RAMON decryption on a software defined radio. The programming of this hardware is done in LabVIEW which allows for controlling the built-in transceiver modules. However, first measurements show that the decryption takes 51 s. This is because LabVIEW is not suitable for handling very large numbers like they are utilized in cryptography. Because such a long processing time is not feasible in experiments nor in a real-life scenarios, this method is not suitable for a prototyping platform. Thus, a different approach is chosen to optimize the decryption processing time. LabVIEW still provides the framework for handling the protocol and controlling the transceivers, but the decryption is performed in a Java application. In that way, the entire decryption process takes only about 2.2 ms, which is 23,318 times faster than the implementation in LabVIEW. Thus, this new approach meets the necessary timing requirements and is suitable for realistic application scenarios. The shown method allows development and testing of new functionalities in UHF RFID systems but may also be employed in any application that require long processing times in LabVIEW. Furthermore, the implementation of decryption features is the first necessary step towards a fully compliant, crypto enabled interrogator for UHF RFID, featuring a high adaptability.

Moiré superlattices in van der Waals heterostructures represent a highly tunable quantum system, attracting substantial interest in both many-body physics and device applications. However, the influence of the moiré potential on light-matter interactions at room temperature has remained largely unexplored. In our study, we demonstrate that the moiré potential in MoS 2 /WSe 2 heterobilayers facilitates the localization of interlayer exciton (IX) at room temperature. By performing reflection contrast spectroscopy, we demonstrate the importance of atomic reconstruction in modifying intralayer excitons, supported by the atomic force microscopy experiment. When decreasing the twist angle, we observe that the IX lifetime becomes longer and light emission gets enhanced, indicating that non-radiative decay channels such as defects are suppressed by the moiré potential. Moreover, through the integration of moiré superlattices with silicon single-mode cavities, we find that the devices employing moiré-trapped IXs exhibit a significantly lower threshold, one order of magnitude smaller compared to the device utilizing delocalized IXs. These findings not only encourage the exploration of many-body physics in moiré superlattices at elevated temperatures but also pave the way for leveraging these artificial quantum materials in photonic and optoelectronic applications. The authors observe that the atomic reconstruction in MoS 2 /WSe 2 heterobilayers with large lattice mismatch results in the most significant periodic strain distribution, contributing to the effective localisation of excitons within moiré potential traps at room temperature.

The following case study clarifies how these three different functions of mission are discursively entangled with one another. Mission as a bridge-builder (between people, cultures, and religions of different origin), as a traitor (cooperating with corrupt colonial and imperial powers), and as a victim (finding misery and death on the mission field). Each of these three terms (bridge-builder, traitor, victim) is, to an extent, applicable to the events that took place during the night of 19–20 October 1896 in Akeri on the slopes of Mount Meru (former German East Africa, today Tanzania). Using the concept of entanglement history, I will analyze the death of two young German missionaries of the Lutheran Leipzig Mission, “caught in the crossfire” between the African community to be outreached and the German colonial military. We will see how various symbolic systems collide in the year 1896 at Akeri. The systems are represented by: (1) German Lutheran missions activities; (2) A German colonial and military expedition; and (3) The resistance of African Maasai societies’ leadership. “Akeri 1896” (I will continue to refer to this event specifically as “Akeri 1896” throughout the article) had become in the following 100 years a complex entanglement of metaphoric meanings. The same event can be a placeholder for victory, for defeat, for disaster, for martyrdom, for Christ-centredness (of the missionaries in their own perception), as well as for evil-centredness (the Africans in their perception of the Western foreigners).

Preliminary clinical data suggest that pain reduction through fasting may be effective for different diagnoses. This uncontrolled observational clinical study examined the effects of prolonged modified fasting on pain and functional parameters in hip and knee osteoarthritis. Patients admitted to the inpatient department of Internal Medicine and Nature-based Therapies of the Immanuel Hospital Berlin between February 2018 and December 2020 answered questionnaires at the beginning and end of inpatient treatment, as well as at 3, 6, and 12 months after discharge. Additionally, selected blood and anthropometric parameters, as well as subjective pain ratings, were routinely assessed during the inpatient stay. Fasting was the only common intervention for all patients, being performed as part of a multimodal integrative treatment program, with a daily caloric intake of <600 kcal for 7.7 ± 1.7 days. N = 125 consecutive patients were included. The results revealed an amelioration of overall symptomatology (WOMAC Index score: −14.8 ± 13.31; p < 0.001; d = 0.78) and pain alleviation (NRS Pain: −2.7 ± 1.98, p < 0.001, d = 1.48). Pain medication was reduced, stopped, or replaced by herbal remedies in 36% of patients. Improvements were also observed in secondary outcome parameters, including increased quality of life (WHO-5: +4.5 ± 4.94, p < 0.001, d = 0.94), reduced anxiety (HADS-A: −2.1 ± 2.91, p < 0001, d = 0.55) and depression (HADS-D: −2.3 ± 3.01, p < 0.001, d = 0.65), and decreases in body weight (−3.6 kg ± 1.65, p < 0.001, d = 0.21) and blood pressure (systolic: −6.2 ± 15.93, p < 0.001, d = 0.43; diastolic: −3.7 ± 10.55, p < 0.001, d = 0.43). The results suggest that patients with osteoarthritis of the lower extremities may benefit from prolonged fasting as part of a multimodal integrative treatment to improve quality of life, pain, and disease-specific functional parameters. Confirmatory randomized controlled trials are warranted to further investigate these hypotheses.