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"Flaherty, Ryan"
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A High Voltage Power Supply That Mitigates Current Reversals in Capillary Zone Electrophoresis-Electrospray Mass Spectrometry
by
Sun, Liangliang
,
Flaherty, Ryan J.
,
Brownell, Greg A.
in
Analytical Chemistry
,
Bioinformatics
,
Biotechnology
2017
Capillary electrophoresis coupled with electrospray ionization typically employs two power supplies, one at each end of the capillary. One power supply is located at the proximal (injection) end of the capillary. The power supply located at the distal (detector) end of the capillary drives the electrospray. Electrophoresis is driven by the difference in potential between these power supplies. Separations that employ large capillary inner diameter, high conductivity background electrolyte, and high separation potentials generate higher current than that produced by the electrospray. Excess current flows through the electrospray power supply. Most power supplies are not designed to sink current, and the excess current will cause the electrospray voltage to deviate from its set point. We report a simple circuit to handle this excess current, allowing separations under a wide range of electrophoretic conditions.
Graphical Abstract
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Journal Article
Synthetic Fiber Reinforced Concrete in Marine Environments and Indirect Tension Test
2018
An experiment was conducted to evaluate the durability, toughness, and strength of Synthetic Fiber Reinforced Concrete after being immersed in five separate environments for one year at FAU SeaTech. The specimens were molded and reinforced with two-inch Polypropylene/Polyethylene Fibers in a concrete aggregate matrix and were cut into identical sizes. Some of these environments had accelerated parameters meant to increase degradation to simulate longevity and imitate harsh environments or seawater conditions. The environments consisted of: a high humidity locker (ideal conditions), submerged in the Intracoastal Waterway (FAU barge), seawater immersion, a wet and dry seawater immersion simulating a splash/tidal zone, and another in low pH seawater. The latter three were in an elevated temperature room (87-95°F) which produced more degradative properties. The specimens were monitored and the environments were controlled. The specimens were then evaluated using the IDT test method using force to initiate first-cracking and post-cracking behaviors.
Dissertation
SMTA Members of Distinction Awards Announced
2022
A former VP of Technical Programs on the SMTA Global Board of Directors, Richard has presented numerous award-winning technical papers at SMTA conferences and supported several technical committees over the years. Sherry Stepp has been an advocate for the SMTA on a national, international, and most recently at the local level. Since she joined SMTA in 2009, Sherry has been an important voice with the Marcom Committee, the Women's Leadership Program, and the Expos Committee. Since 2020 she took on leadership roles with her local Huntsville chapter, first as president and most recently as VP of Membership.
Trade Publication Article
Development and improvement of capillary electrophoresis methods and instrumentation
2016
In this work, I present the development and improvement of capillary electrophoresis (CE) methods and instrumentation. Included are advancements made for two-dimensional CE separations, the development and characterization of an online SERS detector for CE, an automated fraction collector for CE separations, a current sinking power supply for electrospray ionization mass spectrometry that is used with a CE instrument, and the development of an instrument and method for high through-put aptamer generation termed 2D-CE-SELEX.
Dissertation
The use of a blended polyimide/polyester (PI/PE) felt for liquid filtration
2005
The purpose of this project was to examine whether a polyimide/polyester composite felt can be used in four liquid filtration processes for the customer, Imerys, International. This was determined by examining its use in the filtering of four different sized products. The trial composite felt was tested against a total 21 other felts based on five test parameters: total filtrate volume, total amount of wet cake produced, percent cake solids, total amount of dry cake produced, and the percent filtrate solids. The hypothesis stated that the trial felt would work well enough in laboratory testing for two of the four products and could be recommended for full scale testing in these two applications. The two products hypothesized to succeed were the Supermite and Atomite products, which have the smallest average particle size of the four. The results of the laboratory testing concluded that the hypothesis was not supported. Although the trial felt filtered both the Snowflake and Supermite products well, they were not the two smallest resulting products. However, the product did perform well enough in these two areas to be recommended for full scale testing, with only the Supermite product making final approvals for pilot plant testing.
Dissertation