Explore the vast range of titles available.

Background It is challenging to diagnose hepatic cirrhosis and hepatocellular carcinoma (HCC) at an early stage since non-invasive markers are not specific and do not identify the early stage. Objective Serum microRNA-192 could represent an early and critical pathogenetic factor in different liver diseases. Methods 92 participants were allocated into four equal groups ( n  = 23): control, compensated liver cirrhosis, decompensated cirrhosis, and HCC groups. Results Decompensated cirrhosis and HCC showed significantly elevated Serum Alanine aminotransferase, aspartate aminotransferase, bilirubin, alpha-fetoprotein, and microRNA-192. Conclusion Serum microRNA-192 can predict decompensated liver cirrhosis and HCC with high sensitivity and specificity.