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1 result(s) for "Kachurak, Kara"
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Oncolytic HSV-1 G207 Immunovirotherapy for Pediatric High-Grade Gliomas
Oncolytic HSV-1 G207 Immunovirotherapy for Pediatric High-Grade Gliomas
by Totsch, Stacie , Nan, Li , Bag, Asim K in Adolescent , Adolescents , Adverse events
2021
A neurotropic herpes simplex virus that was genetically inactivated to prevent replication in normal cells was injected into the brain tumors of 12 patients with tumors that had progressed during previous treatment. Eleven patients had some radiographic or clinical responses, with inflammation detected in some PET scans. The median survival was 12.2 months, and 4 of 11 patients were still alive 18 months after treatment.
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