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Like Morrison and the Doors, Marcus likes to set the reader up and then go his own way, and when I say he's a writer's writer, I mean that he has a knack for saying whatever he wants but in a way only he can pull off. [...] in mid-book he riffs on lesser-known bands (Moby Grape) and movies (\"Pump Up the Volume\") and completely obscure novels (Wayne Wilson's \"Loose Jam\").

Multiply this scene a thousand times and you'd have the raw material for a documentary on the chitlin' circuit, that string of venues where black entertainers not only made a decent living in a segregated time but also honed their chops and got ready to raise the curtain on a new sound called rock 'n' roll.

The 47-song Witmark demos (so called after M. Witmark & Sons, Dylan's first publishing company) present the unfiltered Dylan, the man with nothing but his guitar and harmonica and occasionally a piano on which he chunks out the chords guitar-style; on \"Mr. Tambourine Man,\" there's the distinct sound of a foot keeping time.

Writing about art theft, Robert K. Wittman - who founded the Federal Bureau of Investigation's art crime team - paints a portrait of his former employer, and it isn't a pretty one.

A poem called \"Walking\" has as its epigraph the words \"Music's a wood you walk through\" (from novelist David Mitchell), and here the poet walks through the music she makes of her own experiences, her lines swelling and falling as she thinks of Chekhov, Tolstoy, Rachmaninoff, a gift from an old friend, the cup of tea she hopes to have later, and, of course, a certain mythological canine.

Talk of a large, new Costco store planned for West 23d Street so alarmed community leaders that they began mobilizing against the plan even though it was only a rumor. On Friday, the rumor was confirmed.

Fibroblast growth factor (FGF) 19 is an enterokine synthesized and released when bile acids are taken up into the ileum. We show that FGF19 stimulates hepatic protein and glycogen synthesis but does not induce lipogenesis. The effects of FGF19 are independent of the activity of either insulin or the protein kinase Akt and, instead, are mediated through a mitogen-activated protein kinase signaling pathway that activates components of the protein translation machinery and stimulates glycogen synthase activity. Mice lacking FGF15 (the mouse FGF19 ortholog) fail to properly maintain blood concentrations of glucose and normal postprandial amounts of liver glycogen. FGF19 treatment restored the loss of glycogen in diabetic animals lacking insulin. Thus, FGF19 activates a physiologically important, insulin-independent endocrine pathway that regulates hepatic protein and glycogen metabolism.

Aims/Introduction Diabetes is a global issue that currently affects 425 million people worldwide. One observable microvascular complication of this condition is a change in the foveal avascular zone (FAZ). In this study, we used optical coherence tomography angiography to investigate the effect of diabetes on the FAZ. Materials and Methods A total of 11 participants with diabetes and 11 participants without diabetes took part in this study. Participants in both groups were matched for age (P = 0.217) and sex (P = 0.338), and had no history of ocular disease. Macular optical coherence tomography angiography (OCT‐A) scans of participants’ right and left eyes were taken. Glycosylated hemoglobin (HbA1c) and blood glucose levels were also measured. The FAZ area was manually segmented at the levels of the superficial capillary plexus (FAZSCP) and deep capillary plexus (FAZDCP). Results There was a strong relationship between the FAZ area of participants’ right and left eyes (P ≤ 0.001) in both diabetes and non‐diabetes groups. In the diabetes group, the FAZSCP (P = 0.047) and FAZDCP (P = 0.011) areas was significantly larger than in the non‐diabetes group. Moreover, multiple linear regression analysis predicted a 0.07‐mm2 increase in the FAZSCP and FAZDCP areas of individuals with diabetes for every 1% increase in their HbA1c level. Conclusions Our findings show that there is enlargement of the FAZ in individuals with diabetes compared with individuals without diabetes. In the diabetes group, this enlargement appears to be correlated with HbA1c level. OCT‐A imaging could, therefore, be a useful tool to monitor the FAZ and identify potential early microvasculopathy in diabetes. One observable microvascular complication of diabetes is a change in the foveal avascular zone (FAZ). We have found that there is enlargement of the FAZ in individuals with diabetes, as assessed using optical coherence tomography angiography (OCT‐A); this enlargement appears to be correlated with long‐term glycemic control. OCT‐A imaging could be a useful tool to monitor theFAZ and identify potential early microvasculopathy in individuals with diabetes.

Efficient catalysts play a pivotal role in advancing eco-friendly water treatment strategies, particularly in the removal of diverse organic contaminants found in water-petroleum sources. This study addresses the multifaceted challenges posed by contaminants, encompassing a spectrum of heavy metals such as As, Cd, Cr, Mn, Mo, Ni, Pb, Sb, Se, and Zn alongside pollutants like oily water (OIW), total suspended solids (TSS), chemical oxygen demand (COD), dyes, and pharmaceuticals, posing threats to both aquatic and terrestrial ecosystems. Herein, we present the synthesis of biogenically derived Mn@NiO nanocomposite (NC) photocatalysts, a sustainable methodology employing an aqueous Rosmarinus officinalis L. extract, yielding particles with a size of 36.7 nm. The catalyst demonstrates exceptional efficacy in removing heavy metals, achieving rates exceeding 99–100% within 30 min, alongside notable removal efficiencies for OIW (98%), TSS (87%), and COD (98%). Furthermore, our photodegradation experiments showed remarkable efficiencies, with 94% degradation for Rose Bengal (RB) and 96% for methylene blue (MB) within 120 min. The degradation kinetics adhere to pseudo-first-order behavior, with rate constants of 0.0227 min −1 for RB and 0.0370 min −1 for MB. Additionally, the NC exhibits significant antibiotic degradation rates of 97% for cephalexin (CEX) and 96% for amoxicillin (AMOX). The enhanced photocatalytic performance is attributed to the synergistic interplay between the Mn and NiO nanostructures, augmenting responsiveness to sunlight while mitigating electron-hole pair recombination. Notably, the catalyst demonstrates outstanding stability and reusability across multiple cycles, maintaining its stable nanostructure without compromise. Graphical Abstract

Annotation of biomedical entities with widely used, well-structured ontologies and ontology-aware tools ensures data and analyses are Findable, Accessible, Interoperable, and Reusable (FAIR). Standardized terms with synonyms support lexical search, while ontology structure enables biologically meaningful grouping of annotations, such as by location and type. However, ontologies serving diverse communities are often more complex than needed for specific applications, creating barriers to adoption by researchers and resource developers. For example, cell atlases often attempt simplifications by manually building term hierarchies linking to cell type and anatomy ontologies, but these may include relationship types unsuitable for grouping annotations. We present tools for validating human expert curated term hierarchies, developed in two human reference atlas projects, against ontology structures. The tools provide tabular statistics plus graphical views of matching and non-matching terms and relationships to support discussion and conflict resolution. The HuBMAP Human Reference Atlas (HRA) effort is used to validate the approach and tools, and the Human Developmental Cell Atlas is featured as a use case.