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Identifying the relationship between academic stress and mental health of undergraduate university students is crucial for reducing and understanding its negative effects, enhancing students' ability to cope with stressful situations, and thereby reducing the harm it causes on academic performance and overall well-being. This study aims to examine the correlation and predictive value of academic stress on mental health in undergraduate university students. A representative sample of 1,265 undergraduate university students from a private university in Bolivia was assessed using Pearson's correlation analysis to determine the predictive value of academic stress on mental health. To validate the measurements obtained, a stepwise Hierarchical Multiple Linear Regression analysis was applied. A probability model was estimated to identify academic stressors that contribute to the probability of students experiencing Languishing Mental Health. The study revealed that Self-inflicted Stress was the most significant stressor among undergraduate students. This indicates that students' self-demands and self-efficacy perceptions are essential factors in the development of high academic stress levels. There is a clear correlation between high levels of academic stress and the probability of experiencing Languishing Mental Health.

Virtual communities are essential in contemporary social and organizational domains. Their sustainability is largely propelled by members’ contributions, and yet the mechanisms for achieving significant participation remain ambiguous. Grounded in the Technology Acceptance Model, our primary objective is to identify the factors that may predict the intention to participate in a virtual community of practice; secondly, we aim to detect the most influential predictor(s) and the best model. In this paper, we conduct a cross-sectional study with a sample of 114 virtual community participants. Our multiple and weighted regression analyses reveal that technological, personal, and motivational factors sway participation intentions. Nevertheless, a combination of specific factors, interactivity, self-efficacy, and identification, are the most closely related to participation intention. This research offers valuable insights for organizations and community promoters, enhancing member retention and interaction stimulation and thereby constructing sustainable virtual environments through effective community design and management.

Background: The shortage of donor kidneys has prompted interest in using organs from donors with severe acute kidney injury (AKI), but robust data on outcomes from donors with AKIN stage 3 remain limited. Methods: This single-centre, retrospective cohort study compared outcomes of kidney transplants from deceased donors with AKIN stage 3 AKI to matched non-AKI donors (n = 57 per group; matched by donor age ±5 years, year of transplant, and major cardiovascular risk factors). Primary outcomes were delayed graft function (DGF), death-censored graft survival, and patient survival. Secondary outcomes included renal function at follow-up. Results: DGF occurred in 54.4% (31/57) of AKIN 3 recipients vs. 33.3% (19/57) of non-AKI recipients (risk difference 21.1%, 95% CI 3.1–39.2; p = 0.037). Five-year death-censored graft survival was 94.7% vs. 96.4% (HR 1.28, 95% CI 0.25–6.52; p = 0.645). Five-year patient survival was 84.8% vs. 84.0% (HR 0.96, 95% CI 0.30–3.05; p = 0.979). Median follow-up was 32 months. Conclusions: In this preliminary, selected kidneys from AKIN stage 3 donors yielded similar medium-term graft and patient survival to non-AKI donors, despite higher DGF incidence. Findings should be interpreted cautiously and confirmed in adequately powered, multicentre studies with extended follow-up.

(ProQuest: ... denotes non-USASCII text omitted.) En el presente trabajo nos centramos en el individualismo en la poesía romántica en la China moderna,1 la expresión del individuo y la voz individual en el proceso de desarrollo del romanticismo en este país2, echando una mirada hacia España, un país cuya literatura romántica es relativamente tardía y breve en Europa. Sin embargo, en el siguiente estudio observaremos que ambos países tienen influencias exteriores semejantes en cuanto a su romanticismo y producen temas y estilos similares, aunque también gozan de diferencias en sus respectivas creaciones poéticas románticas a causa de distintas tradiciones sociales, literarias y culturales. Esas diferencias y sus razones históricas se explorarán a continuación. España presencia el auge de su propio Romanticismo con bastante retraso por tener una etapa agitada, cuando sufre eventos como la Guerra de Independencia, dos restauraciones de absolutismo, y la primera Guerra Carlista, entre muchos otros. Los intelectuales se exilian a países como Inglaterra o Francia, donde nacen nuevas ideas románticas, y las traen a España al terminar la censura ideológica. Al otro lado del mundo, China en su época moderna tiene una experiencia similar, aunque con un retraso de casi un siglo: en la etapa final de la sociedad feudal china, la dinastía Qing (Ж) se encuentra en una situación convulsa y problemática. Así podemos decir que el romanticismo de España y de China en su época moderna comparten el mismo origen, y por lo tanto resulta natural que se produzcan obras con rasgos parecidos, entre los cuales destaca la expresión del individuo, espíritu nuclear del Romanticismo europeo. Por lo tanto, resulta natural que esta tendencia importada del extranjero experimente filtración cultural y adaptación literaria autóctona, y deje marcas peculiares en las obras chinas y las distinga de las de origen occidental. En el espíritu del Aldridge, las obras literarias en un estudio comparativo no son necesariamente rapports de fait. \"[***] Comparative may be used in literary study to indicate affinity, tradition, or influence. Affinity consists in resemblances in style, structure, mood, or idea between two works which have no other connection\" (5). Además, como señala un antiguo modismo chino, piedras de otros cerros pueden servir para pulir el jade? es decir, las cualidades de otros nos ayudan a mejorar lo propio, consideramos que una mirada hacia los poco estudiados poetas románticos españoles en China contribuirá a crear nuevas perspectivas y ayudará a tener una nueva comprensión de la literatura propia. La expresión libre del sentimiento y la pasión individual, que caracterizan al Romanticismo europeo, concuerdan con el requerimiento del movimiento del Cuatro de Mayo y así promovieron fuertemente la liberación y el descubrimiento de la autoconciencia de la nación china de principios del siglo XX. Berlin señala en su libro que, \"[...] the free untrammeled will and the denial of the fact that there is a nature of things, the attempt to blow up and explode very notion of a stable structure of anything [...] are the deepest and in a sense the most insane elements in this extremely valuable and important movement\" (117). Eso explica por qué los literatos exageran la voluntad individual como muestra del triunfo de la libertad, entre los cuales destaca José de Espronceda, que era, al principio, exigente con la realidad, esforzándose por una república liberal, y luego, desterrado y desengañado al no poder amoldarse a la vida real.

Based on the concept of linguistic distance (Santos Gargallo, 1993) and the transfer/ interfere hypothesis (Kellerman, 1977), it can be said that the long linguistic distance between Chinese and Spanish implies great difficulties for Chinese learners in learning Spanish as a foreign language (ELE). However, Chinese university students generally possess a good command of English (L2), which lies between Chinese (LM) and Spanish (L3) in the linguistic sequence (Lu, 2008, p. 48) and the L2 can have a positive influence on L3 learning. To corroborate this positive influence, combining the methods of contrastive analysis (AC) and error analysis (AE), the present research studies the usage of Spanish participles. A questionnaire has been designed based on the AC of Spanish and English participles, and 50 examples of the usage of Spanish participles by Chinesespeaking university students have been collected. The subsequent result of the AE ratifies the beneficial role of L2 on L3 learning. In addition, it has been quantitatively proven that positive transfer occurs prominently in basic and intermediate level usages, while interference is notably present in the advanced level. Keywords: ELE Methodology for Chinese speakers, Linguistic distance, Participle, Spanish-English contrastive study, Error analysis

Basándose en el concepto de distancia lingüística (Santos Gargallo, 1993; Moreno, 2010) y la hipótesis de transferencia / interferencia (Kellerman, 1977; Kellerman et al, 1986), se puede decir que la larga distancia lingüística entre el chino y el español implica muchas dificultades para los aprendices chinos por falta de apoyo de fenómenos lingüísticos conocidos en su lengua materna (LM). Sin embargo, un posible factor favorable es que los estudiantes universitarios chinos generalmente poseen un buen dominio de inglés, que se encuentra entre el chino, su lengua materna, y el español, su tercera lengua, en la secuencia de la distancia lingüística (Lu, 2008, p. 48). Nuestra hipótesis es que las similitudes entre el inglés y el español producen transferencia positiva, mientras que las diferencias generan interferencia. Tras un estudio contrastivo de los participios en español e inglés, el presente trabajo estudia el uso que hacen los estudiantes universitarios chinos del participio en español y se realiza un análisis de errores (AE). El resultado del AE ratifica nuestra hipótesis, y además, hemos descubierto que la transferencia positiva se presenta destacadamente en los usos de niveles básico e intermedio, mientras que la interferencia se presenta principalmente en el nivel avanzado.

Background: The management of metastatic hormone-sensitive prostate cancer (mHSPC) has evolved with the integration of androgen receptor signaling inhibitors (ARSIs) and metastasis-directed therapies (MDTs). Stereotactic body radiotherapy (SBRT) offers precise local control, yet real-world data on its combination with apalutamide remain limited. Methods: We conducted a multicenter retrospective cohort study including 134 patients with mHSPC treated with apalutamide and SBRT between February 2021 and December 2024. The primary endpoints were progression-free survival (PFS), local control (LC), and treatment safety. PSA kinetics and radiologic response were evaluated, and outcomes were analyzed according to PSA thresholds and treatment timing. Results: Most patients (93.3%) had low-volume disease; 97.1% presented with ≤5 metastases. At a median follow-up of 28 months, LC was 99.3% and 95.5% of patients were progression-free. Complete radiological response was achieved in 87.5% of patients, and 68.4% attained ultralow PSA levels (≤0.02 ng/mL). Undetectable PSA and radiologic complete response were independently associated with improved PFS (p = 0.010 and p = 0.011, respectively). Treatment was well tolerated, with grade ≥3 toxicity occurring in only 2.2% of patients. Conclusions: The combination of apalutamide and SBRT in mHSPC is associated with high local and systemic disease control and minimal toxicity in a real-world setting. This approach may delay systemic treatment intensification and the onset of castration resistance. Prospective studies are warranted to confirm these findings.

This study examines the incidence of academic stress and its determinants on mental health among university students. It employs a comparative approach to evaluate the role of academic stress as a predictor of mental health outcomes during and after the COVID-19 pandemic. Utilizing a mixed-methods approach, the research surveyed students using standardized instruments to measure academic stress and mental health. Cross-sectional analyses were conducted at two time points, drawing on responses from undergraduate students at a private university in Latin America. The primary objectives were to quantify academic stress levels and their stressors, evaluate mental health status, and explore this relationship during these periods. Data collection yielded 1,265 and 707 valid responses for each respective period, employing the Academic Stress Inventory and the Mental Health Continuum-Short Form for assessments. Findings indicated high stress levels among students, regardless of the pandemic phase, with notable stressors including teacher, exam, results, group work, peer, time management, and self-inflicted stress. The post-pandemic phase revealed changes in the impacts of stressors, with self-inflicted stress, group work, and time management stress showing significant relevance to mental health. The study highlights the challenge of academic stress on mental health, urging educational institutions to address pressures and provide support mechanisms for student well-being.

Meningococcal disease continues to be a global public health concern due to its epidemic potential, severity, and sequelae. The global epidemiological data on circulating meningococcal serogroups have never been reviewed concurrently with the laboratory capacity for meningococcal surveillance at the national level. We, therefore, aimed to conduct a country-level review of meningococcal surveillance, serogroup distribution, and vaccine use. We conducted a systematic literature review across six databases to identify studies (published January 1, 2010 to October 16, 2017) and grey literature reporting meningococcal serogroup data for the years 2010-2016. We performed independent random effects meta-analyses for serogroups A, B, C, W, X, Y, and other. We developed and circulated a questionnaire-based survey to surveillance focal points in countries (N = 95) with known regional bacterial meningitis surveillance programs to assess their surveillance capacity and summarized using descriptive methods. We included 173 studies from 59 countries in the final analysis. The distribution of meningococcal serogroups differed markedly between countries and regions. Meningococcal serogroups C and W accounted for substantial proportions of meningococcal disease in most of Africa and Latin America. Serogroup B was the predominant cause of meningococcal disease in many locations in Europe, the Americas, and the Western Pacific. Serogroup Y also caused many cases of meningococcal disease in these regions, particularly in Nordic countries. Survey responses were received from 51 countries. All countries reported the ability to confirm the pathogen in-country, while approximately 30% either relied on reference laboratories for serogrouping (N = 10) or did not serogroup specimens (N = 5). Approximately half of countries did not utilize active laboratory-based surveillance system (N = 22). Nationwide use of a meningococcal vaccine varied, but most countries (N = 36) utilized a meningococcal vaccine at least for certain high-risk population groups, in private care, or during outbreaks. Due to the large geographical variations in circulating meningococcal serogroups, each country should continue to be monitored for changes in major disease-causing serogroups in order to inform vaccine and control policies. Similarly, laboratory capacity should be appropriately scaled up to more accurately understand local epidemiology and disease burden, as well as the impact of vaccination programs.

Androgen deprivation therapy (ADT) is a fundamental component of treatment for metastatic hormone-sensitive prostate cancer (mHSPC), but it accelerates bone mineral density loss and increases fracture risk. International guidelines recommend calcium and vitamin D supplementation, baseline dual-energy X-ray absorptiometry (DXA), and antiresorptive therapy in patients with osteoporosis. We conducted a retrospective review of 156 mHSPC patients treated with ADT at a tertiary hospital between January 2022 and December 2024. We assessed adherence to guideline-recommended bone health measures. Collected variables included age, ADT duration, calcium/vitamin D supplementation, DXA testing, antiresorptive treatment, and fracture events. Exploratory stratified analyses were performed, and proportions were reported with 95% confidence intervals (CIs). Calcium/vitamin D supplementation was prescribed in 50.6% of patients (95% CI: 42.9-58.4), baseline DXA was performed in 12.8% (95% CI: 8.5-18.9), and denosumab was administered in 5.1% of the cohort (95% CI: 2.6-9.8). The median follow-up was 23 months, with a fracture incidence of 0.67 events per 100 person-years. Stratified analyses showed lower adherence in older patients, those with prolonged ADT exposure, and those with high metastatic burden. Adherence to guideline-recommended bone health measures in patients with mHSPC receiving ADT was markedly suboptimal. These findings underscore the need to implement standardized institutional protocols to ensure systematic supplementation, routine DXA monitoring, and appropriate antiresorptive therapy.