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8
result(s) for
"Mazori, Daniel R."
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Paradoxical granulomatous reaction to ustekinumab
by
Femia, Alisa N.
,
Caplan, Avrom S.
,
Flamm, Alexandra
in
Biopsy
,
Case reports
,
Conflicts of interest
2024
Sarcoidosis is a multisystem disorder characterised by granulomatous inflammation affecting various organs. The skin is commonly involved and can serve as an initial indicator of disease. While the precise aetiology of sarcoidosis remains elusive, evidence suggests involvement of T‐helper type (TH)‐1 and TH‐17 pathways. Psoriasis shares common inflammatory pathways with sarcoidosis, prompting the repurposing of biologic therapies approved for psoriasis for off‐label treatment of cutaneous sarcoidosis. However, this approach has raised concerns due to the development of granulomatous eruptions in some patients. We present a case of a patient with psoriasis who was diagnosed with systemic sarcoidosis while on ustekinumab. We review previous cases of ustekinumab‐associated sarcoidosis and discuss the challenges associated with utilising biologic agents originally intended for psoriasis treatment for sarcoidosis. Sarcoidosis is a multisystem disorder characterised by granulomatous inflammation affecting various organs. While the precise aetiology of sarcoidosis remains elusive, evidence suggests involvement of T‐helper type (TH)‐1 and TH‐17 pathways. Psoriasis shares common inflammatory pathways with sarcoidosis, prompting the repurposing of biologic therapies approved for psoriasis for off‐label treatment of cutaneous sarcoidosis. We present a case of a patient with psoriasis who was diagnosed with systemic sarcoidosis while on ustekinumab and review previous cases of ustekinumab‐associated sarcoidosis. Indication of the Figure (1) and (2) (1) annular plaques on cheek of cutaneous sarcoidosis (2) skin histopathology demonstrating sarcoidal granulomas in the dermis
Journal Article
Response to “The Role of Patient‐ and Drug‐Related Factors in Oral Minoxidil and Pericardial Effusion: Analyses of Data From the United States Food and Drug Administration Adverse Event Reporting System”
by
Lo Sicco, Kristen
,
Garshick, Michael
,
Shapiro, Jerry
in
alopecia
,
Correspondence
,
hypertension
2025
Journal Article
Correction to: Pseudovasculitis: an etiology not to miss
2021
A correction to this paper has been published: 10.1007/s10067-021-05615-9
Journal Article