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result(s) for
"Messemaker, Marja"
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Nosocomial Mycobacterium bovis–Bacille Calmette-Guérin Infections Due to Contamination of Chemotherapeutics: Case Finding and Route of Transmission
by
Man, Peter de
,
Vos, Margreet C.
,
Deutekom, Henk van
in
Adolescent
,
Adult
,
Antineoplastic Agents - therapeutic use
2003
We studied nosocomial infections due to Mycobacterium bovis bacille Calmette-Guérin (BCG) Onco-TICE bacteria, transmitted by contamination of medication prepared in BCG Onco-TICE–contaminated hoods in the pharmacy, in 5 immunocompromised patients at 3 hospitals. The BCG strains cultured from the patients had the same DNA profile as the BCG Onco-TICE strain used for bladder instillation. To prevent these infections, a change from open to closed preparation was made; strictly separated preparation in time of BCG Onco-TICE instillation and chemotherapy was enforced, the biological safety cabinet was disinfected between preparations, and gloves were changed between preparations
Journal Article