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\"Flexibility with produce fixturing is crucial for maximizing sales and ensuring that the product offering remains relevant to customer demands, seasonality and trends,\" observes Jeff Cady, VP, produce and floral for Schenectady, N.Y.-based Northeast Shared Services, the main operating company of Tops Markets LLC and Price Chopper/Market 32. Stores that depend on showcasing local produce benefit significantly from modular fixturing such as orchard bins on casters, spillover bins and Euro tables. Smart shelving is still in the testing stage for most chains (Kroger has begun testing a solution with Microsoft that stores and processes volumes of data generated by customer actions on and around the shelves), but adoption is likely to increase.

\"Freshly sliced deli grab-and-go offerings continue to be an area of growth, meeting consumer demands for convenience while [enabling the] purchase [of] high-quality products,\" says Talbert. According to Prach, retailers are adding more pre-packaged offerings that are assembled on-site or through a commissary. Key Takeaways * Bold new flavors, limited-edition products and a greater variety of prepared foods are key drivers in the deli section. * To offset labor shortages, retailers are responding with more grab-and-go cases and fewer service cases in the deli. * Staffing difficulties and demands for convenience are resulting in more remote deli orders.

Futher, a majority of these purchases are impulse buys \"Consumers want to focus their daily diet on the best-tasting products, leading to a shift from center store packaged goods to in-store bakery items that are fresher andmore indulgent,\" says Brant Cash, managing director at New York-based global investment bank Harris Williams. Lakeland, Fla.-based Publix Super Markets recently debuted Italian-inspired Tutto Pugliese bread, made exclusively from durum wheat semolina flour and certified sourdough flour,which are typically used to make pasta. Since many baked goods, such as cookies and brownies, travel very well through delivery channels, Wisloski suggests that supermarkets can take a cue from restaurants that are capturing impulse sales of baked goods with \"add to order\" reminders on their platforms. At Dom's Kitchen & Market location in Chicago's Lincoln Park neighborhood, customers can choose from a variety of Bond Roman-style pizzas, including Potato & Mozzarella, Ricotta Zucchini, Sopressata, Spicy Eggplant, Sun Dried Tomato Arugula, and Mushroom Rosa.

[...]retailers are investing heavily in foodservice. [...]82% of U.S. retailers are increasing space for fresh-prepared grab-and-go meals, according to Tammy Gonzales, senior marketing manager, deli and prepared entrees at Wayzata, Minn.-based Cargill. According to Golub, the chain has had great success with special limited-time offers and is continually \"looking for the next opportunity to meet the moment for our customers.\" [...]61% of consumers are interested in Latin cuisine for the variety of flavors its recipes inspire.

Focus on Digestibility Lactose-free milk is one segment experiencing a surge among health-conscious consumers, due to its lower calorie content and easier digestibility, according to research from Future Market Insights. According to Bailey, availability of A2 milk products is good news for the millions of consumers who have trouble digesting milk. Among smaller companies, Austin, Texas-based frozen treat brand GoodPop has expanded into the beverage aisle with Mini Cans, lunchbox-size 7.5-ounce drinks made with real fruit juice and sparkling water, but no added sugars, sweeteners or flavors.

Ewing sarcoma (ES) is the second most frequent childhood bone cancer driven by the EWS/FLI1 (EF) fusion protein. Genetically defined ES models are needed to understand how EF expression changes bone precursor cell differentiation, how ES arises and through which mechanisms of inhibition it can be targeted. We used mesenchymal Prx1-directed conditional EF expression in mice to study bone development and to establish a reliable sarcoma model. EF expression arrested early chondrocyte and osteoblast differentiation due to changed signaling pathways such as hedgehog, WNT or growth factor signaling. Mesenchymal stem cells (MSCs) expressing EF showed high self-renewal capacity and maintained an undifferentiated state despite high apoptosis. Blocking apoptosis through enforced BCL2 family member expression in MSCs promoted efficient and rapid sarcoma formation when transplanted to immunocompromised mice. Mechanistically, high BCL2 family member and CDK4, but low P53 and INK4A protein expression synergized in Ewing-like sarcoma development. Functionally, knockdown of Mcl1 or Cdk4 or their combined pharmacologic inhibition resulted in growth arrest and apoptosis in both established human ES cell lines and EF-transformed mouse MSCs. Combinatorial targeting of survival and cell cycle progression pathways could counteract this aggressive childhood cancer.

Nielsen IQ data cited in FMI - The Food Industry Association's most recent \"Power of Foodservice\" report shows that deli prepared food dollar and unit sales grew in 2022, along with purchase frequency among heavy buyers. According to Hill, since prepared food and catering items are typically some of the most profitable items sold in-store, retailers have an opportunity to expand their offering for customers, grow loyalty and enhance their businesses overall. The Kroger Co., based in Cincinnati, has become the biggest sushi retailer in the United States, according to a recent report in The Wall Street Journal, while its Home Chef roasted chicken products are \"wildly popular\" with consumers, since these products \"offer convenient and healthy options at affordable prices,\" says Teresa Sabatino, director of customer marketing at Home Chef.

An amendment to this paper has been published and can be accessed via a link at the top of the paper.An amendment to this paper has been published and can be accessed via a link at the top of the paper.