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Medical report of the male patient Blood group ABO B Rh Positive Hematological report HGB (Hemoglobin) (cyanomethanoglobin method) 13.0 g/dL ESR (westergren) 35 mm Differential count WBC Total count of WBC 5300/cmm Neutrophils 43% Lymphocytes 48% Eosinophils 3% Monocytes 6% Basophils 0% Total count of platelet 210 000/cmm Biochemical analysis report Random plasma glucose 5.8 mmol/L S. Creatinine 0.9 mg/dL SGPT (ALT) 32 U/L Immunology report D-Dimer 0.21 Case 2: Medical report of the female patient Hematological report HGB (hemoglobin) (cyanomethanoglobin method) 11.5 g/dL ESR (westergren) 20 mm Differential count WBC Total count of WBC 8200/cmm Neutrophils 57% Lymphocytes 35% Eosinophils 6% Monocytes 2% Basophils 0% Total count of platelet 1,86 000/cmm Biochemical analysis report S. Bilirubin 0.8 mg/dL SGPT (ALT) 32 U/L SGOT (AST) 45 Immunology report D-Dimer Not done Partial sequencing of the RBD portion of the spike protein revealed two featured mutations (L452R and T478K) of the B.1.617.2 PANGO lineage for both samples. 14 Whole-genome sequences revealed 38 mutations and 29 aa substitutions for the sample JUST1 (Collected from the female patient, GISAID accession ID—EPI_ISL_ 2 036 272) and 33 mutations and 26 aa substitutions for sample JUST2 (Collected from the male patient, GISAID accession ID—EPI_ISL_1942249). [...]the Nextstrain server (https://nextstrain.org/sars-cov-2/) for SARS-CoV-2 phylodynamics also bolstered our interpretation based on the mutation pattern of the strains. The Delta variants were 50% more transmissible and 60% more lethal (For every one death 1.6 death in ratio compared with the previous version of the virus) with reduced affinity for neutralizing antibody (The L452R mutation confers a reduction of the recognition capability of the immune system) as demonstrated by other studies. 15,16 Transmission of these new variants may cause a similar impact among Bangladeshi population, which introduced the Oxford-Astrazeneca vaccine.