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428 result(s) for "Shaw, Jon"
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The transport debate
An introduction to the transport debate from two experts in the field, following members of the Smith family as they uncover a wide array of transport issues.
Children Exposed to War/Terrorism
This paper reviews the prevalence of psychological morbidities in children who have been exposed to war-related traumas or terrorism as well as the diversity of war-related casualties and their associated psychological responses. The psychological responses to war-related stressors are categorized as (1) little or no reaction, (2) acute emotional and behavioral effects, and (3) long-term effects. Specific categories of war-related casualties discussed include refugee status, traumatic bereavement, effects of parental absence, and child soldiers. Psychological responses associated with terrorism and bioterrorism are presented. Lastly, mediators of the psychological response to war-related stressors are discussed, to include exposure effects, gender effects, parental, family and social factors, and child-specific factors. Children exposed to war-related stressors experience a spectrum of psychological morbidities including posttraumatic stress symptomatology, mood disorders, externalizing and disruptive behaviors, and somatic symptoms determined by exposure dose effect. Specific questions for future research are identified.
A review of Leishmania infections in American Phlebotomine sand flies – Are those that transmit leishmaniasis anthropophilic or anthropportunists?
Understanding why Diptera, such as mosquitoes and sand flies, feed on humans is crucial in defining them as vectors of diseases such as malaria, dengue fever, Zika virus, and leishmaniasis. Determining their attraction to humans (anthropophily) helps in assessing the risk of disease transmission, designing effective vector control strategies, and monitoring the effectiveness of existing control measures. An important question is whether they are specifically attracted to humans in preference to other mammals or whether there is something else at play. In this paper, I propose that the idea that saying species are “anthropophilic” when they are preferentially attracted to humans is misleading and that such species are generalists that will opportunistically feed on a wide range of animals including humans when they are available. Other species are specialists that, under rare circumstances, accidently feed on humans. For these groups, I propose the names anthropportunists and anthroaccidentalists, respectively. The level of contact depends on a range of environmental factors and it is these that must be considered in evaluating potential vector importance and management. In this paper, I propose a review of the Leishmania identified in American sand flies and relate them to these two concepts and how it is linked to taxonomic groups, evolution, and ecology. There are records of Leishmania in 91 species, which is only 16.5% of American sand fly species. Of these infections, 56.7% are in the genera Lutzomyia, Nyssomyia, Pintomyia , and Psychodopygus , which are typically generalist anthropportunists. Of the species considered to be proven vectors, 77.4% belong to these four genera. As infections were detected by a variety of methods, further case-by-case field studies are required to evaluate the vectorial role of many of the sand fly species in which Leishmania have been found. Comprendre pourquoi les diptères, tels que les moustiques et les phlébotomes, se nourrissent de l’homme est essentiel pour les définir comme vecteurs de maladies telles que le paludisme, la dengue, le virus Zika et la leishmaniose. Déterminer leur attirance pour l’homme (anthropophilie) permet d’évaluer le risque de transmission de maladies, de concevoir des stratégies efficaces de lutte antivectorielle et de surveiller l’efficacité des mesures de contrôle existantes. La question est de savoir s’ils sont spécifiquement attirés par l’homme plutôt que par d’autres mammifères, ou existe-t-il un autre concept sous-jacent ? Dans cet article, je propose que l’idée selon laquelle les espèces sont préférentiellement attirées par l’homme lorsqu’on les qualifie d’« anthropophiles » est trompeuse et que ces espèces sont généralistes et se nourrissent opportunément d’un large éventail d’animaux, y compris l’homme lorsqu’il est disponible. D’autres sont des spécialistes qui, dans de rares cas, se nourrissent accidentellement de l’homme. Pour ces groupes, je propose respectivement les termes anthropoportunistes et anthropoaccidentels. Le niveau de contact dépend de divers facteurs environnementaux, et ce sont ces derniers qui doivent être pris en compte pour évaluer l’importance potentielle du vecteur et sa gestion. Cet article passe en revue les Leishmania identifiées chez les phlébotomes américains et les relie à ces deux concepts, ainsi qu’à leurs liens avec les groupes taxonomiques, l’évolution et l’écologie. On a recensé des Leishmania dans 91 espèces, soit seulement 16,5 % des espèces de phlébotomes américains. Parmi ces infections, 56,7 % concernent les genres Lutzomyia , Nyssomyia , Pintomyia et Psychodopygus , qui sont typiquement anthropoportunistes généralistes. Parmi les espèces considérées comme vecteurs avérés, 77,4 % appartiennent à ces quatre genres. Les infections ayant été détectées par diverses méthodes, des études de terrain supplémentaires, au cas par cas, sont nécessaires pour évaluer le rôle vectoriel de nombreuses espèces de phlébotomes chez lesquelles des Leishmania ont été trouvées.
Cycling and Sustainability
Explores the reasons for difficulties in making cycling mainstream in many cultures, despite its claims for being one of the most sustainable forms of transport. This title examines the cultural development of cycling in countries with high use and the differences in use between different sub-groups of the population.
One Health Approach to Leishmaniases: Understanding the Disease Dynamics through Diagnostic Tools
Leishmaniases are zoonotic vector-borne diseases caused by protozoan parasites of the genus Leishmania that affect millions of people around the globe. There are various clinical manifestations, ranging from self-healing cutaneous lesions to potentially fatal visceral leishmaniasis, all of which are associated with different Leishmania species. Transmission of these parasites is complex due to the varying ecological relationships between human and/or animal reservoir hosts, parasites, and sand fly vectors. Moreover, vector-borne diseases like leishmaniases are intricately linked to environmental changes and socioeconomic risk factors, advocating the importance of the One Health approach to control these diseases. The development of an accurate, fast, and cost-effective diagnostic tool for leishmaniases is a priority, and the implementation of various control measures such as animal sentinel surveillance systems is needed to better detect, prevent, and respond to the (re-)emergence of leishmaniases.
Multiple Vantage Points on the Mental Health Effects of Mass Shootings
The phenomenon of mass shootings has emerged over the past 50 years. A high proportion of rampage shootings have occurred in the United States, and secondarily, in European nations with otherwise low firearm homicide rates; yet, paradoxically, shooting massacres are not prominent in the Latin American nations with the highest firearm homicide rates in the world. A review of the scientific literature from 2010 to early 2014 reveals that, at the individual level, mental health effects include psychological distress and clinically significant elevations in posttraumatic stress, depression, and anxiety symptoms in relation to the degree of physical exposure and social proximity to the shooting incident. Psychological repercussions extend to the surrounding affected community. In the aftermath of the deadliest mass shooting on record, Norway has been in the vanguard of intervention research focusing on rapid delivery of psychological support and services to survivors of the “Oslo Terror.” Grounded on a detailed review of the clinical literature on the mental health effects of mass shootings, this paper also incorporates wide-ranging co-author expertise to delineate: 1) the patterning of mass shootings within the international context of firearm homicides, 2) the effects of shooting rampages on children and adolescents, 3) the psychological effects for wounded victims and the emergency healthcare personnel who care for them, 4) the disaster behavioral health considerations for preparedness and response, and 5) the media “framing” of mass shooting incidents in relation to the portrayal of mental health themes.
High Resolution Melting Analysis Targeting hsp70 as a Fast and Efficient Method for the Discrimination of Leishmania Species
Protozoan parasites of the genus Leishmania cause a large spectrum of clinical manifestations known as Leishmaniases. These diseases are increasingly important public health problems in many countries both within and outside endemic regions. Thus, an accurate differential diagnosis is extremely relevant for understanding epidemiological profiles and for the administration of the best therapeutic protocol. Exploring the High Resolution Melting (HRM) dissociation profiles of two amplicons using real time polymerase chain reaction (real-time PCR) targeting heat-shock protein 70 coding gene (hsp70) revealed differences that allowed the discrimination of genomic DNA samples of eight Leishmania species found in the Americas, including Leishmania (Leishmania) infantum chagasi, L. (L.) amazonensis, L. (L.) mexicana, L. (Viannia) lainsoni, L. (V.) braziliensis, L. (V.) guyanensis, L. (V.) naiffi and L. (V.) shawi, and three species found in Eurasia and Africa, including L. (L.) tropica, L. (L.) donovani and L. (L.) major. In addition, we tested DNA samples obtained from standard promastigote culture, naturally infected phlebotomines, experimentally infected mice and clinical human samples to validate the proposed protocol. HRM analysis of hsp70 amplicons is a fast and robust strategy that allowed for the detection and discrimination of all Leishmania species responsible for the Leishmaniases in Brazil and Eurasia/Africa with high sensitivity and accuracy. This method could detect less than one parasite per reaction, even in the presence of host DNA.
Community transport, social capital and social exclusion in rural areas
The concept of social capital has been used by numerous authors to investigate various topics. As yet, however, little attention has been paid to its relationship with mobility and social exclusion. Those findings which have been published suggest that the maintenance of social capital and associated networks within and between communities largely depends on mobility, but that local social networks are being undermined as a result of growing car ownership and use. This paper draws on the results of recent rural transport research to suggest that, at the same time, strong local social capital appears important in conferring mobility on certain social groups, especially those without access to a car. In the context of community transport, our analysis uses a geographic framework to attempt to explore these positions and reviews arising policy and research implications.
Observations of Multiple Young-of-the-Year to Juvenile White Sharks (Carcharodon carcharias) within South-West Australian Waters and Its Implications for a Potential Nursery Area(s)
The white shark (Carcharodon carcharias) is a globally distributed top predator. Due to its ecological importance, increasing knowledge through continued research can enhance management measures. One such facet of biological knowledge is the identification of shark nursery areas, as protection of these regions is critical to species survival. Presently, there are two known C. carcharias nursery areas in association with the Eastern Australian subpopulation; however, a nursery area associated with the Southern-Western Australian C. carcharias subpopulation has yet to be identified. Herein, we report opportunistic laser photogrammetry, stereo-photogrammetry, and baited remote underwater video systems (BRUVS) data that resulted in the identification of sixteen young-of-the-year (YOY)-juvenile C. carcharias from two separate regions (i.e., Salisbury Island and Daw Island) in South-West Australia. Additionally, anecdotal bycatch data associated with two YOY C. carcharias (i.e., 1.40 and 1.70 m total length) from another location within the Great Australian Bight are reported. While it is premature to conclude that these sites represent discrete or an expansive interconnected nursery area, the sightings success in this study is indicative that future research may want to consider implementing a study during a similar time period (i.e., February–March) while using a similar attractant methodology (i.e., bottom-set BRUVS baited with squid [Sepioteuthis australis]) to help elucidate the unique life-history characteristics of this C. carcharias subpopulation.